Styrene

Styrene

SCHEMBL8083641

C=C(C)C(=O)OCCO.C=CC(=O)OCC(CC)CCCC.C=Cc1ccccc1

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.56
ALDH1A1 P00352 6/20 0.45
CYP3A4 P08684 3/20 0.45
CA2 P00918 1/20 0.45
TDP1 Q9NUW8 3/20 0.43
LMNA P02545 3/20 0.42
MAPK1 P28482 3/20 0.42
PRSS1 P07477 1/20 0.41
PRSS2 P07478 1/20 0.41
PRSS3 P35030 1/20 0.41
HSD17B10 Q99714 1/20 0.37
ATM Q13315 1/20 0.36
HPGD P15428 1/20 0.34
THRB P10828 1/20 0.33
KDM4E B2RXH2 1/20 0.33
POLB P06746 1/20 0.32
APEX1 P27695 1/20 0.32
HTT P42858 1/20 0.32
RECQL P46063 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL7717059 0.94 TSHR (0.58) TSHRALDH1A1CYP3A4CA2TDP1
Styrene SCHEMBL9510287 0.94 TSHR (0.53) TSHRALDH1A1CYP3A4CA2TDP1
Styrene SCHEMBL27492545 0.93 TSHR (0.57) TSHRALDH1A1CYP3A4CA2TDP1
Styrene SCHEMBL11253457 0.93 TSHR (0.52) TSHRALDH1A1CYP3A4CA2TDP1
Styrene SCHEMBL8956089 0.90 TSHR (0.55) TSHRALDH1A1CYP3A4CA2TDP1
Styrene SCHEMBL29157682 0.90 TSHR (0.60) TSHRALDH1A1CYP3A4CA2TDP1
Styrene SCHEMBL1765871 0.89 TSHR (0.57) TSHRALDH1A1CYP3A4CA2TDP1
Styrene SCHEMBL2352031 0.89 TSHR (0.59) TSHRALDH1A1CYP3A4CA2TDP1
Styrene SCHEMBL1091500 0.89 TSHR (0.52) TSHRALDH1A1CYP3A4CA2TDP1
Styrene SCHEMBL27467831 0.89 TSHR (0.64) TSHRALDH1A1CYP3A4CA2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1041434-A1 Heat-developable photosensitive material FUJI PHOTO FILM CO., LTD. (JP) 2000-10-04 EP disclosed