Styrene

Styrene

SCHEMBL1765871

C=C(C)C(=O)OCC(C)C.C=CC(=O)OCC(CC)CCCC.C=Cc1ccccc1

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.57
ALDH1A1 P00352 6/20 0.46
CYP3A4 P08684 3/20 0.46
CA2 P00918 1/20 0.46
LMNA P02545 3/20 0.45
MAPK1 P28482 3/20 0.45
TDP1 Q9NUW8 3/20 0.44
PRSS1 P07477 1/20 0.42
PRSS2 P07478 1/20 0.42
PRSS3 P35030 1/20 0.42
HSD17B10 Q99714 1/20 0.38
ATM Q13315 1/20 0.37
KDM4E B2RXH2 1/20 0.33
RECQL P46063 1/20 0.33
HPGD P15428 1/20 0.33
MEN1 O00255 1/20 0.32
MAPT P10636 1/20 0.32
KMT2A Q03164 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
THRB P10828 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL2352031 0.92 TSHR (0.59) TSHRALDH1A1CYP3A4CA2LMNA
Styrene SCHEMBL8956089 0.91 TSHR (0.55) TSHRALDH1A1CYP3A4CA2LMNA
Styrene SCHEMBL7717059 0.91 TSHR (0.58) TSHRALDH1A1CYP3A4CA2LMNA
Styrene SCHEMBL1246542 0.91 ALDH1A1 (0.54) TSHRALDH1A1CYP3A4CA2LMNA
Styrene SCHEMBL7760829 0.90 TSHR (0.57) TSHRALDH1A1CYP3A4CA2LMNA
Styrene SCHEMBL5952124 0.90 TSHR (0.57) TSHRALDH1A1CYP3A4CA2LMNA
Styrene SCHEMBL27467831 0.90 TSHR (0.64) TSHRALDH1A1CYP3A4CA2LMNA
Styrene SCHEMBL8083641 0.89 TSHR (0.56) TSHRALDH1A1CYP3A4CA2LMNA
Styrene SCHEMBL28988056 0.89 ALDH1A1 (0.50) TSHRALDH1A1CYP3A4CA2LMNA
Styrene SCHEMBL10579599 0.89 ALDH1A1 (0.52) TSHRALDH1A1CYP3A4CA2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180092362-A1 COMPOSITIONS, METHODS OF MAKING A COMPOSITION, AND METHODS OF USE UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. 2018-04-05 US disclosed
US-20170042162-A1 COMPOSITIONS, METHODS OF MAKING A COMPOSITION, AND METHODS OF USE UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (US) 2017-02-16 US disclosed
EP-1625279-B1 SELF ADAPTIVE CEMENT SYSTEMS SERVICES PETROLIERS SCHLUMBERGER (FR) 2016-06-22 EP disclosed
US-8551244-B2 Self adaptive cement systems SCHLUMBERGER TECHNOLOGY CORPORATION (US) 2013-10-08 US disclosed
US-20110120715-A1 SELF ADAPTIVE CEMENT SYSTEMS LE ROY-DELAGE SYLVAINE 2011-05-26 US disclosed
EP-2199539-A1 Self adaptive cement systems Services Pétroliers Schlumberger (FR) 2010-06-23 EP disclosed
US-20070137528-A1 Self adaptive cement systems SCHLUMBERGER TECHNOLOGY CORPORATION 2007-06-21 US disclosed
EP-1625279-A1 SELF ADAPTIVE CEMENT SYSTEMS SERVICES PETROLIERS SCHLUMBERGER (FR) 2006-02-15 EP disclosed
WO-2004101951-A1 SELF ADAPTIVE CEMENT SYSTEMS SERVICES PETROLIERS SCHLUMBERGER (FR) 2004-11-25 WO disclosed