SCHEMBL8083858

SCHEMBL8083858

CCCCC(CC)C(=O)OCCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.49

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CA2 P00918 7/20 0.49
CA1 P00915 4/20 0.49
MAPK1 P28482 1/20 0.41
ATM Q13315 2/20 0.37
GAA P10253 1/20 0.37
XBP1 P17861 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
CYP3A4 P08684 1/20 0.32
TSHR P16473 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8752111 1.00 CA2 (0.49) CA2CA1MAPK1ATMGAA
SCHEMBL8752093 0.92 CA2 (0.40) CA2CA1MAPK1
SCHEMBL24603122 0.91 HDAC1 (0.38) CA2CA1NPSR1CYP3A4TSHR
SCHEMBL8752147 0.90 MAPT (0.38) CA2CA1
SCHEMBL12793529 0.84 CA1 (0.33) CA2CA1ATMTSHR
SCHEMBL13649271 0.81
SCHEMBL18267327 0.81
SCHEMBL18412469 0.79
SCHEMBL2759389 0.79
SCHEMBL8402511 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2000273067-A FLUORINE-CONTAINING ESTER COMPOUND KAO CORP 2000-10-03 JP disclosed