Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 8/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | TYMP | P19971 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8079087 | 0.93 | NPC1 (0.34) | HTR2ADNM1MEN1KMT2AALDH1A1 | |
| SCHEMBL10446746 | 0.85 | CYP19A1 (0.38) | HTR2AMEN1KMT2AALDH1A1TSHR | |
| Hexane SCHEMBL27851252 | 0.85 | CYP19A1 (0.38) | HTR2AMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL1687611 | 0.83 | TSHR (0.42) | HTR2ADNM1MEN1KMT2AALDH1A1 | |
| SCHEMBL27299525 | 0.83 | TSHR (0.42) | HTR2ADNM1MEN1KMT2AALDH1A1 | |
| SCHEMBL28164639 | 0.83 | TSHR (0.42) | HTR2ADNM1MEN1KMT2AALDH1A1 | |
| SCHEMBL26406724 | 0.81 | TSHR (0.40) | HTR2ADNM1MEN1KMT2AALDH1A1 | |
| SCHEMBL26028589 | 0.80 | HTR2A (0.43) | HTR2ADNM1MEN1KMT2AALDH1A1 | |
| SCHEMBL24017146 | 0.79 | TSHR (0.38) | HTR2ADNM1MEN1KMT2AALDH1A1 | |
| SCHEMBL9506529 | 0.79 | CYP19A1 (0.35) | TSHRCYP19A1TYMP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0634403-B1 | N-polyhalobenzyl-pyrazole carboxamides endowed with acaricidal and insecticidal activity | ISAGRO SPA (IT) | 2000-09-13 | — | — | EP | disclosed |
| US-5541214-A | N-polyhalobenzyl-pyrazole carboxamides endowed with acaricidal and insecticidal activity | ISAGRO S.P.A. (IT) | 1996-07-30 | — | — | US | disclosed |
| EP-0634403-A1 | N-polyhalobenzyl-pyrazole carboxamides endowed with acaricidal and insecticidal activity | ISAGRO S.p.A. (IT) | 1995-01-18 | — | — | EP | disclosed |