Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 5/20 | 0.76 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.76 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.76 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.76 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.76 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.76 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.76 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.76 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.76 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.76 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.76 |
| ▸ | AAK1 | Q2M2I8 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | FPR1 | P21462 | 1/20 | 0.48 |
| ▸ | PADI2 | Q9Y2J8 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8115559 | 0.87 | HDAC6 (1.00) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL14345841 | 0.86 | HDAC1 (0.74) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL4058179 | 0.85 | ALDH1A1 (0.62) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL8079286 | 0.83 | HDAC3 (0.70) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL8117254 | 0.81 | HDAC3 (0.67) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL9130537 | 0.79 | AAK1 (0.59) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL9130527 | 0.79 | AAK1 (0.59) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL8972594 | 0.79 | HDAC3 (0.59) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL8117247 | 0.78 | HDAC6 (0.63) | HDAC1HDAC6HDAC3HDAC4HDAC7 | |
| SCHEMBL8103245 | 0.78 | HDAC3 (0.62) | HDAC1HDAC6HDAC3HDAC4HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009026701-A1 | SIRTUIN INHIBITORS | METHYLGENE INC. (CA) | 2009-03-05 | — | — | WO | disclosed |