Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 3/20 | 0.47 |
| ▸ | CIT | O14578 | 1/20 | 0.47 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.47 |
| ▸ | PRKCB | P05771 | 1/20 | 0.47 |
| ▸ | PRKCA | P17252 | 1/20 | 0.47 |
| ▸ | PRKACA | P17612 | 1/20 | 0.47 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.47 |
| ▸ | MARK3 | P27448 | 1/20 | 0.47 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.47 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.47 |
| ▸ | CLK1 | P49759 | 1/20 | 0.47 |
| ▸ | GSK3A | P49840 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | CDK9 | P50750 | 1/20 | 0.47 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.47 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.47 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.47 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.47 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8079377 | 0.84 | CIT (0.68) | ROCK2CITPRKD3MAP4K4PRKCB | |
| SCHEMBL8070094 | 0.83 | ROCK2 (0.51) | ROCK2CITPRKD3MAP4K4PRKCB | |
| SCHEMBL1554050 | 0.82 | ROCK2 (0.69) | ROCK2CITPRKD3MAP4K4PRKCB | |
| SCHEMBL1552873 | 0.82 | ROCK2 (0.69) | ROCK2CITPRKD3MAP4K4PRKCB | |
| Hydrochloric Acid SCHEMBL8080142 | 0.81 | ROCK2 (0.70) | ROCK2CITPRKD3MAP4K4PRKCB | |
| SCHEMBL6557937 | 0.81 | ROCK2 (0.53) | ROCK2CITPRKD3MAP4K4PRKCB | |
| SCHEMBL8070012 | 0.80 | ROCK2 (0.53) | ROCK2CITPRKD3MAP4K4PRKCB | |
| SCHEMBL1553901 | 0.80 | ROCK2 (0.52) | ROCK2CITPRKD3MAP4K4PRKCB | |
| Hydrochloric Acid SCHEMBL6560287 | 0.80 | ROCK2 (0.69) | ROCK2CITPRKD3MAP4K4PRKCB | |
| Hydrochloric Acid SCHEMBL6560283 | 0.80 | ROCK2 (0.69) | ROCK2CITPRKD3MAP4K4PRKCB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6156766-A | Benzamide compounds and pharmaceutical use thereof | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 2000-12-05 | — | — | US | disclosed |