Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 2/20 | 0.37 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | RAD52 | P43351 | 2/20 | 0.32 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | KHK | P50053 | 3/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 2/20 | 0.31 |
| ▸ | CCR5 | P51681 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8089831 | 0.87 | MAPKAPK2 (0.48) | MAPKAPK2GAARAD52MEN1KMT2A | |
| SCHEMBL8088244 | 0.87 | MAPKAPK2 (0.38) | HTR7MAPKAPK2GAARAD52MEN1 | |
| SCHEMBL8084113 | 0.86 | MAPKAPK2 (0.38) | HTR7MAPKAPK2GAARAD52MEN1 | |
| SCHEMBL8089999 | 0.85 | SLC2A1 (0.39) | MAPKAPK2ALDH1A1NPSR1 | |
| SCHEMBL8088300 | 0.83 | MAPKAPK2 (0.37) | HTR7MAPKAPK2GAARAD52MITF | |
| SCHEMBL8084729 | 0.76 | SMN1; SMN2 (0.40) | GAAMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL8084787 | 0.76 | KMT2A (0.39) | MEN1KMT2AKDM4EALDH1A1RXFP1 | |
| SCHEMBL8076742 | 0.74 | QPCT (0.41) | GAAKMT2AKDM4EALDH1A1RXFP1 | |
| SCHEMBL8084411 | 0.72 | KMT2A (0.37) | MAPKAPK2MEN1KMT2AKDM4ERXFP1 | |
| SCHEMBL8089824 | 0.72 | PRNP (0.34) | MEN1KMT2AKDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057447-A | BACTERICIDES FOR CAMPYLOBACTER | ZENYAKU KOGYO KABUSHIKI KAISHA (JP) | 2000-05-02 | — | — | US | disclosed |
| EP-0926139-A1 | QUINOLINE SULFIDE DERIVATIVES | ZENYAKU KOGYO KABUSHIKIKAISHA (JP) | 1999-06-30 | — | — | EP | disclosed |