Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | PRKDC | P78527 | 10/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.36 |
| ▸ | PLK4 | O00444 | 1/20 | 0.36 |
| ▸ | CCNC | P24863 | 1/20 | 0.36 |
| ▸ | CDK8 | P49336 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RAC1 | P63000 | 1/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8088244 | 0.91 | MAPKAPK2 (0.38) | PRKDCMAPKAPK2ALDH1A1CCNCCDK8 | |
| SCHEMBL8084113 | 0.90 | MAPKAPK2 (0.38) | PRKDCMAPKAPK2ALDH1A1NPSR1CCNC | |
| SCHEMBL8089831 | 0.89 | MAPKAPK2 (0.48) | MAPKAPK2CCNCCDK8 | |
| SCHEMBL8088300 | 0.86 | MAPKAPK2 (0.37) | MAPKAPK2 | |
| SCHEMBL8084133 | 0.85 | HTR7 (0.37) | MAPKAPK2ALDH1A1NPSR1 | |
| SCHEMBL8084787 | 0.79 | KMT2A (0.39) | ALDH1A1 | |
| SCHEMBL8076742 | 0.78 | QPCT (0.41) | ALDH1A1MAPK1 | |
| SCHEMBL8089824 | 0.76 | PRNP (0.34) | ALDH1A1MAPTMAPK1 | |
| SCHEMBL8084411 | 0.76 | KMT2A (0.37) | MAPKAPK2TP53MAPT | |
| SCHEMBL8084729 | 0.76 | SMN1; SMN2 (0.40) | ALDH1A1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057447-A | BACTERICIDES FOR CAMPYLOBACTER | ZENYAKU KOGYO KABUSHIKI KAISHA (JP) | 2000-05-02 | — | — | US | disclosed |
| EP-0926139-A1 | QUINOLINE SULFIDE DERIVATIVES | ZENYAKU KOGYO KABUSHIKIKAISHA (JP) | 1999-06-30 | — | — | EP | disclosed |