SCHEMBL8084293

SCHEMBL8084293

CCCCC[SiH](CCC(=O)OCC)c1ccc(C)cc1

nearest known ligand 0.38

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 3/20 0.38
CYP4A11 Q02928 3/20 0.38
PPARG P37231 1/20 0.38
PPARA Q07869 1/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
TNF P01375 2/20 0.37
DGKA P23743 1/20 0.37
CYP1A2 P05177 1/20 0.37
GAA P10253 1/20 0.36
HSD17B10 Q99714 1/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
P2RX3 P56373 2/20 0.36
MAPT P10636 2/20 0.36
KDM4E B2RXH2 1/20 0.36
GLA P06280 1/20 0.36
HPGD P15428 1/20 0.36
CCKBR P32239 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8083686 0.90 CYP4F2 (0.41) CYP4F2CYP4A11MEN1KMT2ASMN1; SMN2
SCHEMBL8084483 0.89 SMN1; SMN2 (0.43) CYP4F2CYP4A11PPARGPPARAMEN1
SCHEMBL8076400 0.85 CYP4F2 (0.41) CYP4F2CYP4A11MEN1KMT2ASMN1; SMN2
SCHEMBL8076419 0.78 SMN1; SMN2 (0.47) CYP4F2CYP4A11MEN1KMT2ASMN1; SMN2
SCHEMBL8472618 0.76 HTT (0.38) SMN1; SMN2L3MBTL1HPGD
P-Xylene SCHEMBL29008697 0.74 CYP4F2 (0.52) CYP4F2CYP4A11MEN1KMT2ASMN1; SMN2
SCHEMBL8076437 0.71 AKR1B1 (0.44) PPARGPPARAMEN1KMT2AHSD17B10
Toluene SCHEMBL4749551 0.71 CYP4F2 (0.55) CYP4F2CYP4A11SMN1; SMN2DGKAMAPT
Toluene SCHEMBL6270207 0.71 CYP4F2 (0.55) CYP4F2CYP4A11SMN1; SMN2DGKAMAPT
Toluene SCHEMBL28845143 0.71 CYP4F2 (0.55) CYP4F2CYP4A11SMN1; SMN2DGKAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0673942-B1 Silacyclohexanone compounds as intermediates for the preparation of silacyclohexane-type liquid cristal compounds SHINETSU CHEMICAL CO (JP) 2000-11-08 EP disclosed
EP-0673942-A1 Silacyclohexanone compounds as intermediates for the preparation of silacyclohexane-type liquid cristal compounds Shin-Etsu Chemical Co., Ltd. (JP) 1995-09-27 EP disclosed