Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | TOP2A | P11388 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | TNF | P01375 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8076419 | 0.90 | SMN1; SMN2 (0.47) | SMN1; SMN2CYP4F2CYP4A11ALDH1A1CYP3A4 | |
| SCHEMBL8084293 | 0.89 | CYP4F2 (0.38) | SMN1; SMN2CYP4F2CYP4A11GAAKDM4E | |
| SCHEMBL8076437 | 0.83 | AKR1B1 (0.44) | ALDH1A1MEN1KMT2APTPN1PPARG | |
| SCHEMBL418321 | 0.79 | LTA4H (0.38) | SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8076410 | 0.79 | SMN1; SMN2 (0.50) | SMN1; SMN2CYP4F2CYP4A11ALDH1A1ALOX5 | |
| SCHEMBL9643720 | 0.78 | DNM1 (0.40) | SMN1; SMN2MEN1KMT2A | |
| SCHEMBL418038 | 0.78 | DNM1 (0.40) | SMN1; SMN2MEN1KMT2A | |
| SCHEMBL415280 | 0.78 | DNM1 (0.40) | SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8992386 | 0.78 | DNM1 (0.40) | SMN1; SMN2MEN1KMT2A | |
| Benzoic Acid SCHEMBL6130381 | 0.76 | CES2 (0.54) | SMN1; SMN2CYP4F2CYP4A11ALDH1A1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-7309878-A | — | — | None | — | — | JP | disclosed |
| EP-0673942-B1 | Silacyclohexanone compounds as intermediates for the preparation of silacyclohexane-type liquid cristal compounds | SHINETSU CHEMICAL CO (JP) | 2000-11-08 | — | — | EP | disclosed |
| JP-H07309878-A | SILACYCLOHEXANONE COMPOUND AND PRODUCTION OF SILACYCLOHEXANE-TYPE LIQUID CRYSTAL COMPOUND USING THE SILACYCLOHEXANONE COMPOUND | SHIN ETSU CHEM CO LTD | 1995-11-28 | — | — | JP | disclosed |
| EP-0673942-A1 | Silacyclohexanone compounds as intermediates for the preparation of silacyclohexane-type liquid cristal compounds | Shin-Etsu Chemical Co., Ltd. (JP) | 1995-09-27 | — | — | EP | disclosed |