Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 6/20 | 0.52 |
| ▸ | SRD5A1 | P18405 | 5/20 | 0.52 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | SHBG | P04278 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8084449 | 1.00 | SRD5A2 (0.52) | SRD5A2SRD5A1DDB1CRBNAR | |
| SCHEMBL8023123 | 0.85 | SRD5A1 (0.53) | SRD5A2SRD5A1AR | |
| SCHEMBL8016811 | 0.83 | SRD5A2 (0.49) | SRD5A2SRD5A1AR | |
| SCHEMBL8096297 | 0.82 | SRD5A1 (0.55) | SRD5A2SRD5A1 | |
| SCHEMBL8096293 | 0.82 | SRD5A1 (0.55) | SRD5A2SRD5A1 | |
| SCHEMBL8092620 | 0.79 | SRD5A1 (0.52) | SRD5A2SRD5A1 | |
| SCHEMBL8092618 | 0.79 | SRD5A1 (0.52) | SRD5A2SRD5A1 | |
| SCHEMBL8996777 | 0.78 | SRD5A2 (0.52) | SRD5A2SRD5A1ARSHBG | |
| SCHEMBL8018780 | 0.78 | SRD5A2 (0.47) | SRD5A2SRD5A1AR | |
| SCHEMBL8016817 | 0.78 | SRD5A2 (0.43) | SRD5A2SRD5A1ARSHBG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0756481-B1 | 17$g(b)-ARYL-4-AZA-STEROID DERIVATIVES | MERCK & CO INC (US) | 2000-12-27 | — | — | EP | disclosed |
| EP-0756481-A4 | 17-g(b)-ARYL-4-AZA-STEROID DERIVATIVES | MERCK & CO INC (US) | 1998-11-18 | — | — | EP | disclosed |
| EP-0756481-A1 | 17$g(b)-ARYL-4-AZA-STEROID DERIVATIVES | MERCK & CO. INC. (US) | 1997-02-05 | — | — | EP | disclosed |
| US-5525608-A | ANTIACNE AGENT, SKIN DISORDERS, GLANDULAR DISORDERS | MERCK & CO., INC. (US) | 1996-06-11 | — | — | US | disclosed |
| WO-1995028928-A1 | 17β-ARYL-4-AZA-STEROID DERIVATIVES | MERCK & CO., INC. (US) | 1995-11-02 | — | — | WO | disclosed |