Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | CA2 | P00918 | 4/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | MMP14 | P50281 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10719655 | 0.92 | TSHR (0.59) | TSHRCYP3A4TDP1ATMALDH1A1 | |
| SCHEMBL6657558 | 0.92 | TSHR (0.63) | TSHRCYP3A4TDP1ATMALDH1A1 | |
| SCHEMBL22404812 | 0.87 | TSHR (0.58) | TSHRCYP3A4TDP1ATMALDH1A1 | |
| SCHEMBL6656496 | 0.87 | TSHR (0.58) | TSHRCYP3A4TDP1ATMALDH1A1 | |
| SCHEMBL28581685 | 0.86 | TSHR (0.56) | TSHRCYP3A4TDP1ATMALDH1A1 | |
| SCHEMBL7788704 | 0.85 | CYP3A4 (0.62) | TSHRCYP3A4TDP1ATMALDH1A1 | |
| SCHEMBL257295 | 0.84 | CYP3A4 (0.70) | TSHRCYP3A4TDP1ATMALDH1A1 | |
| SCHEMBL16772 | 0.83 | TSHR (0.61) | TSHRCYP3A4TDP1ATMALDH1A1 | |
| SCHEMBL1269088 | 0.83 | TSHR (0.61) | TSHRCYP3A4TDP1ATMALDH1A1 | |
| SCHEMBL5444856 | 0.83 | TSHR (0.56) | TSHRCYP3A4TDP1ATMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9670331-B2 | Poly vinyl chloride foam promoters | PMC ORGANOMETALLIX, INC. (US) | 2017-06-06 | — | — | US | disclosed |
| EP-2334718-B1 | POLY VINYL CHLORIDE FOAM PROMOTERS | PMC ORGANOMETALLIX INC (US) | 2016-02-17 | — | — | EP | disclosed |
| EP-1652881-B1 | Thermal stabilizer compositions for halogen-containing vinyl polymers | ROHM & HAAS (US) | 2011-11-23 | — | — | EP | disclosed |
| US-20110172320-A1 | POLY VINYL CHLORIDE FOAM PROMOTERS | ARKEMA INC. (US) | 2011-07-14 | — | — | US | disclosed |
| EP-2334718-A1 | POLY VINYL CHLORIDE FOAM PROMOTERS | Arkema, Inc. (US) | 2011-06-22 | — | — | EP | disclosed |
| WO-2010033549-A1 | POLY VINYL CHLORIDE FOAM PROMOTERS | ARKEMA INC. (US) | 2010-03-25 | — | — | WO | disclosed |
| US-7531587-B2 | Thermal stabilizer composition for halogen-containing vinyl polymers | ROHM AND HAAS COMPANY (US) | 2009-05-12 | — | — | US | disclosed |
| US-7488433-B2 | Thermal stabilizer compositions for halogen-containing vinyl polymers | ROHM AND HAAS COMPANY (US) | 2009-02-10 | — | — | US | disclosed |
| US-20070049672-A1 | Thermal stabilizer composition for halogen-containing vinyl polymers | PMC CINCINNATI, INC. | 2007-03-01 | — | — | US | disclosed |
| EP-1621576-B1 | Thermal stabilizer compositions for halogen-containing vinyl polymers | ROHM & HAAS (US) | 2007-02-14 | — | — | EP | disclosed |
| EP-0890608-A2 | A latent mercaptan as a heat stabilizer | MORTON INTERNATIONAL, INC. (US) | 1999-01-13 | — | — | EP | disclosed |
| EP-0866090-A1 | Improved PVC foam compositions | MORTON INTERNATIONAL, INC. (US) | 1998-09-23 | — | — | EP | disclosed |
| US-5786399-A | PVC foam compositions | MORTON INTERNATIONAL, INC. (US) | 1998-07-28 | — | — | US | disclosed |
| US-5783613-A | ORGANOTIN COMPOUNDS AS ACTIVATOR FOR BLOWING AGENT | MORTON INTERNATIONAL, INC. (US) | 1998-07-21 | — | — | US | disclosed |
| EP-0850987-A1 | Improved PVC foam compositions | MORTON INTERNATIONAL, INC. (US) | 1998-07-01 | — | — | EP | disclosed |
| US-5753719-A | ACTIVATOR FOR BLOWING AGENTS | MORTON INTERNATIONAL, INC. (US) | 1998-05-19 | — | — | US | disclosed |
| US-5726213-A | FOAMING VINYL CHLORIDE POLYMER BY HEATING MIXTURE OF POLYMER, BLOWING AGENT, STABILIZER INCLUDING ORGANOTIN MERCAPTIDE OF MERCAPTOALKYL CARBOXYLATE OR SULFIDE THEREOF, OPTIONAL ORGANOTIN SALT | MORTON INTERNATIONAL, INC. (US) | 1998-03-10 | — | — | US | disclosed |
| US-5710188-A | HEATING A MIXTURE OF POLYVINYL CHLORIDE, A BLOWING AGENT, AN ORGANOTIN HALIDE AND A STABILIZER TO FOAM POLYMER | MORTON INTERNATIONAL, INC. (US) | 1998-01-20 | — | — | US | disclosed |
| EP-0742259-A1 | Latent mercaptans as multi-functional additives for halogen-containing polymer compositions | MORTON INTERNATIONAL, INC. (US) | 1996-11-13 | — | — | EP | disclosed |
| EP-0075396-B1 | AQUEOUS COATING COMPOSITIONS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-06-05 | — | — | EP | disclosed |