Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | CA2 | P00918 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | MMP14 | P50281 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6657558 | 0.92 | TSHR (0.63) | TSHRCYP3A4TDP1ATMALDH1A1 | |
| SCHEMBL808445 | 0.87 | TSHR (0.58) | TSHRCYP3A4TDP1ATMALDH1A1 | |
| SCHEMBL22404812 | 0.87 | TSHR (0.58) | TSHRCYP3A4TDP1ATMALDH1A1 | |
| SCHEMBL5487010 | 0.86 | CYP3A4 (0.64) | TSHRCYP3A4TDP1ATMALDH1A1 | |
| Anisole SCHEMBL27699180 | 0.86 | ALDH1A1 (0.54) | TSHRCYP3A4TDP1ATMALDH1A1 | |
| SCHEMBL28581685 | 0.86 | TSHR (0.56) | TSHRCYP3A4TDP1ATMALDH1A1 | |
| SCHEMBL27646671 | 0.86 | TSHR (0.42) | TSHRCYP3A4TDP1ATMALDH1A1 | |
| Methacrylic Acid SCHEMBL4447127 | 0.86 | TSHR (0.56) | TSHRCYP3A4TDP1ATMALDH1A1 | |
| SCHEMBL257295 | 0.84 | CYP3A4 (0.70) | TSHRCYP3A4TDP1ATMALDH1A1 | |
| SCHEMBL16772 | 0.83 | TSHR (0.61) | TSHRCYP3A4TDP1ATMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1123915-B1 | Process for producing alpha, beta-unsaturated carboxylic acid esters and catalyst for use in such process | NIPPON CATALYTIC CHEM IND (JP) | 2004-07-28 | — | — | EP | disclosed |
| EP-1123915-A1 | Process for producing alpha, beta-unsaturated carboxylic acid esters and catalyst for use in such process | Nippon Shokubai Co., Ltd. (JP) | 2001-08-16 | — | — | EP | disclosed |