Sugi Predict

Sugi Predict / Compounds / SCHEMBL8084590

SCHEMBL8084590

SCHEMBL8084590

CCCCOC(=O)c1ccc(Cc2ccccc2)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 6/20 0.64
▸ LMNA P02545 5/20 0.64
▸ MAPK1 P28482 3/20 0.64
▸ CYP1A2 P05177 2/20 0.64
▸ CYP2C19 P33261 2/20 0.64
▸ SMN1; SMN2 Q16637 2/20 0.64
▸ ESR1 P03372 2/20 0.64
▸ CYP2D6 P10635 1/20 0.64
▸ NR1H2 P55055 1/20 0.64
▸ RNASEL Q05823 1/20 0.64
▸ CYP3A4 P08684 3/20 0.62
▸ CYP2C9 P11712 1/20 0.62
▸ PDE4D Q08499 1/20 0.62
▸ ALDH1A1 P00352 4/20 0.60
▸ TDP1 Q9NUW8 3/20 0.60
▸ L3MBTL1 Q9Y468 3/20 0.60
▸ HPGD P15428 1/20 0.56
▸ RECQL P46063 1/20 0.56
▸ NPC1 O15118 1/20 0.55
▸ MAPT P10636 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9233896 0.88 TSHR (0.65) TSHRLMNAMAPK1CYP1A2CYP2C19
SCHEMBL11416620 0.88 TSHR (0.78) TSHRLMNAMAPK1CYP1A2CYP2C19
SCHEMBL1869078 0.87 LMNA (0.79) TSHRLMNAMAPK1CYP1A2CYP2C19
SCHEMBL97514 0.87 LMNA (0.79) TSHRLMNAMAPK1CYP1A2CYP2C19
SCHEMBL28978386 0.87 LMNA (0.79) TSHRLMNAMAPK1CYP1A2CYP2C19
Hydrogen Peroxide SCHEMBL28645617 0.87 ESR1 (0.82) TSHRLMNAMAPK1CYP1A2CYP2C19
SCHEMBL6670120 0.86 TSHR (0.71) TSHRLMNAMAPK1CYP1A2CYP2C19
Dimethylamine SCHEMBL2126244 0.85 LMNA (0.71) TSHRLMNAMAPK1CYP1A2CYP2C19
SCHEMBL10988558 0.85 ESR1 (0.74) TSHRLMNAMAPK1CYP1A2CYP2C19
SCHEMBL23175014 0.85 LMNA (0.76) TSHRLMNAMAPK1CYP1A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4865648-A ELECTRON DONOR DYE; ESTER; PHENOL, CARBOXY ACID, PHOSPHATE ESTER, TRIAZOLE KITO TSUTOMU (JP) 1989-09-12 — — US claimed
US-4720301-A Reversible heat sensitive recording composition PILOT INK CO., LTD. (JP) 1988-01-19 — — US claimed
CN-108329746-B Compounds for reducing background color in color change compositions 西甘产业股份有限公司 2022-08-02 — — CN disclosed
US-11225100-B2 Tunable directional color transition compositions and methods of making and using the same SEGAN INDUSTRIES, INC. (US) 2022-01-18 — — US disclosed
EP-2969582-B1 COMPOUNDS FOR REDUCING BACKGROUND COLOR IN COLOR CHANGE COMPOSITIONS SEGAN IND INC (US) 2021-06-02 — — EP disclosed
CN-111272304-A Lower critical temperature indicator 苏州和萃新材料有限公司 2020-06-12 — — CN disclosed
US-10570294-B2 Compounds for reducing background color in color change compositions SEGAN INDUSTRIES, INC. (US) 2020-02-25 — — US disclosed
US-20190204280-A1 Tunable Directional Color Transition Compositions and Methods of Making and Using the Same SEGAN INDUSTRIES, INC. 2019-07-04 — — US disclosed
US-20190142713-A1 Optical Evanescent Color Change Compositions and Methods of Making and Using the Same SEGAN INDUSTRIES, INC. 2019-05-16 — — US disclosed
CN-109476946-A Optics fadout color-changing composition and its method made and used 西甘产业股份有限公司 2019-03-15 — — CN disclosed
EP-3443042-A1 OPTICAL EVANESCENT COLOR CHANGE COMPOSITIONS AND METHODS OF MAKING AND USING THE SAME Segan Industries, Inc. (US) 2019-02-20 — — EP disclosed
CN-105283317-A Compounds for reducing background color in color change compositions SEGAN IND INC 2016-01-27 — — CN disclosed
EP-2969582-A1 COMPOUNDS FOR REDUCING BACKGROUND COLOR IN COLOR CHANGE COMPOSITIONS Segan Industries, Inc. (US) 2016-01-20 — — EP disclosed
US-9217736-B2 Tunable directional color transition compositions and methods of making and using the same SEGAN INDUSTRIES, INC. (US) 2015-12-22 — — US disclosed
US-20140275381-A1 COMPOUNDS FOR REDUCING BACKGROUND COLOR IN COLOR CHANGE COMPOSITIONS SEGAN INDUSTRIES, INC. 2014-09-18 — — US disclosed
WO-2014144693-A1 COMPOUNDS FOR REDUCING BACKGROUND COLOR IN COLOR CHANGE COMPOSITIONS SEGAN INDUSTRIES, INC. (US) 2014-09-18 — — WO disclosed
US-8569208-B1 Tunable directional color transition compositions and methods of making and using the same SEGAN INDUSTRIES, INC. (US) 2013-10-29 — — US disclosed
US-6165234-A FOR IMPARTING REVERSIBLE COLOR CHANGES TO WAXES AND CANDLES WHEN HEATED OR WHEN WAX MELTS OR WHEN THE CANDLE BURNS KANAKKANATT SEBASTIAN V (US) 2000-12-26 — — US disclosed
US-4865648-A ELECTRON DONOR DYE; ESTER; PHENOL, CARBOXY ACID, PHOSPHATE ESTER, TRIAZOLE KITO TSUTOMU (JP) 1989-09-12 — — US disclosed
US-4720301-A Reversible heat sensitive recording composition PILOT INK CO., LTD. (JP) 1988-01-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190142713-A1 Optical Evanescent Color Change Compositions and Methods of Making and Using the Same ERCC1, XPA, ERCC5 TSHR 3827/4885LMNA 89/4885MAPK1 4031/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.