Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 20/20 | 0.60 |
| ▸ | PDE11A | Q9HCR9 | 14/20 | 0.60 |
| ▸ | PDE10A | Q9Y233 | 10/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13918771 | 0.91 | PDE4B (0.62) | PDE4BPDE11APDE10A | |
| SCHEMBL13919447 | 0.91 | PDE4B (0.53) | PDE4BPDE11APDE10A | |
| SCHEMBL12396146 | 0.91 | PDE4B (0.53) | PDE4BPDE11APDE10A | |
| SCHEMBL12923213 | 0.90 | PDE4B (0.48) | PDE4BPDE11APDE10A | |
| SCHEMBL8230144 | 0.90 | PDE4B (0.57) | PDE4BPDE11APDE10A | |
| SCHEMBL8092859 | 0.90 | PDE4B (0.48) | PDE4BPDE11APDE10A | |
| SCHEMBL691228 | 0.88 | PDE4B (0.58) | PDE4BPDE11APDE10A | |
| SCHEMBL12705538 | 0.87 | PDE4B (0.45) | PDE4BPDE11APDE10A | |
| SCHEMBL12396223 | 0.86 | PDE4B (0.52) | PDE4BPDE11APDE10A | |
| SCHEMBL8275037 | 0.84 | PDE4B (0.70) | PDE4BPDE11APDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009009002-A2 | HYDROGEN CHLORIDE SALT OF A SUBSTITUTED 5-OXAZOL-2-YL-QUINOLINE COMPOUND AND A PROCESS FOR THE PRODUCTION THEREOF | SCHERING CORPORATION (US) | 2009-01-15 | — | — | WO | disclosed |
| WO-2008008327-A2 | XINAFOATE SALT OF A SUBSTITUTED 5-OXAZOL-2-YL-QUINOLINE COMPOUND | SCHERING CORPORATION (US) | 2008-01-17 | — | — | WO | disclosed |