Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 20/20 | 0.58 |
| ▸ | PDE11A | Q9HCR9 | 13/20 | 0.58 |
| ▸ | PDE10A | Q9Y233 | 10/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8084612 | 0.88 | PDE4B (0.60) | PDE4BPDE11APDE10A | |
| SCHEMBL16393759 | 0.88 | PDE4B (0.54) | PDE4BPDE11APDE10A | |
| SCHEMBL16393762 | 0.88 | PDE4B (0.54) | PDE4BPDE11APDE10A | |
| SCHEMBL152336 | 0.88 | PDE4B (0.54) | PDE4BPDE11APDE10A | |
| SCHEMBL152335 | 0.88 | PDE4B (0.54) | PDE4BPDE11APDE10A | |
| SCHEMBL8233465 | 0.83 | PDE4B (0.82) | PDE4BPDE11APDE10A | |
| SCHEMBL12464378 | 0.82 | PDE4B (0.54) | PDE4BPDE11APDE10A | |
| SCHEMBL13919447 | 0.81 | PDE4B (0.53) | PDE4BPDE11APDE10A | |
| SCHEMBL12396146 | 0.81 | PDE4B (0.53) | PDE4BPDE11APDE10A | |
| SCHEMBL12923213 | 0.81 | PDE4B (0.48) | PDE4BPDE11APDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3082708-A1 | MEDIA MILLING PROCESS FOR THE MANUFACTURE OF ACTIVE PHARMACEUTICAL INGREDIENTS IN PROPELLANTS | Merck Sharp & Dohme Corp. (US) | 2016-10-26 | — | — | EP | disclosed |
| WO-2015094927-A1 | MEDIA MILLING PROCESS FOR THE MANUFACTURE OF ACTIVE PHARMACEUTICAL INGREDIENTS IN PROPELLANTS | MERCK SHARP & DOHME CORP. (US) | 2015-06-25 | — | — | WO | disclosed |
| EP-2498847-A1 | DRUG PRODUCTS AND DRY POWDER INHALERS WITH MULTIPLE RESERVOIRS | Merck Sharp & Dohme Corp. (US) | 2012-09-19 | — | — | EP | disclosed |
| EP-2421514-A2 | AGGLOMERATE FORMULATIONS USEFUL IN DRY POWDER INHALERS | Schering Corporation (US) | 2012-02-29 | — | — | EP | disclosed |
| EP-2421518-A2 | AGGLOMERATE FORMULATIONS INCLUDING ACTIVE PHARMACEUTICAL AGENTS WITH TARGETED PARTICLE SIZES | Schering Corporation (US) | 2012-02-29 | — | — | EP | disclosed |
| WO-2010124198-A9 | AGGLOMERATE FORMULATIONS USEFUL IN DRY POWDER INHALERS | SCHERING CORPORATION (US) | 2011-10-13 | — | — | WO | disclosed |
| WO-2011059968-A1 | DRUG PRODUCTS AND DRY POWDER INHALERS WITH MULTIPLE RESERVOIRS | SCHERING CORPORATION (US) | 2011-05-19 | — | — | WO | disclosed |
| WO-2010124198-A2 | AGGLOMERATE FORMULATIONS USEFUL IN DRY POWDER INHALERS | SCHERING CORPORATION (US) | 2010-10-28 | — | — | WO | disclosed |
| WO-2010124203-A2 | AGGLOMERATE FORMULATIONS INCLUDING ACTIVE PHARMACEUTICAL AGENTS WITH TARGETED PARTICLE SIZES | SCHERING CORPORATION (US) | 2010-10-28 | — | — | WO | disclosed |
| EP-2121090-A2 | DISPENSER DOSE COUNTER MECHANISM | SCHERING CORPORATION (US) | 2009-11-25 | — | — | EP | disclosed |
| EP-2099514-A2 | DOSE COUNTER MECHANISM | SCHERING CORPORATION (US) | 2009-09-16 | — | — | EP | disclosed |
| WO-2009086009-A1 | DOSE COUNTERS AND CONTAINERS | SCHERING CORPORATION (US) | 2009-07-09 | — | — | WO | disclosed |
| WO-2008079360-A2 | DISPENSER DOSE COUNTER MECHANISM | SCHERING CORPORATION (US) | 2008-07-03 | — | — | WO | disclosed |
| WO-2008079350-A2 | DOSE COUNTER MECHANISM | SCHERING CORPORATION (US) | 2008-07-03 | — | — | WO | disclosed |