SCHEMBL8084708

SCHEMBL8084708

CCCCC(C)Oc1ccc(C(=O)O)cc1

nearest known ligand 0.59

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.59
TP53 P04637 1/20 0.55
TSHR P16473 1/20 0.55
PLA2G4B P0C869 7/20 0.54
GPR88 Q9GZN0 1/20 0.52
MAPK1 P28482 1/20 0.51
RARB P10826 5/20 0.51
PLA2G4A P47712 1/20 0.49
MAPT P10636 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8434202 1.00 KMT2A (0.59) KMT2ATP53TSHRPLA2G4BGPR88
SCHEMBL8072342 0.95 TP53 (0.58) KMT2ATP53TSHRPLA2G4BGPR88
SCHEMBL8436176 0.95 TP53 (0.58) KMT2ATP53TSHRPLA2G4BGPR88
SCHEMBL5091731 0.94 TP53 (0.60) KMT2ATP53TSHRPLA2G4BMAPK1
SCHEMBL4602775 0.94 TP53 (0.60) KMT2ATP53TSHRPLA2G4BMAPK1
SCHEMBL8081206 0.94 TP53 (0.60) KMT2ATP53TSHRPLA2G4BMAPK1
SCHEMBL13953004 0.94 TP53 (0.60) KMT2ATP53TSHRPLA2G4BMAPK1
SCHEMBL25788012 0.94 TP53 (0.60) KMT2ATP53TSHRPLA2G4BMAPK1
SCHEMBL7691425 0.94 TP53 (0.60) KMT2ATP53TSHRPLA2G4BMAPK1
SCHEMBL9058650 0.94 TP53 (0.60) KMT2ATP53TSHRPLA2G4BMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2958950-B1 AN IMPROVED MAGNESIUM DICHLORIDE SUPPORTED TITANIUM CATALYST COMPOSITION FOR POLYOLEFIN POLYMERIZATION RELIANCE INDUSTRIES LTD (IN) 2019-09-11 EP claimed
US-20160002372-A1 Magnesium Dichloride Supported Titanium Catalyst Composition for Polyolefin Polymerization RELIANCE INDUSTRIES LIMITED (IN) 2016-01-07 US claimed
EP-2958950-A2 AN IMPROVED MAGNESIUM DICHLORIDE SUPPORTED TITANIUM CATALYST COMPOSITION FOR POLYOLEFIN POLYMERIZATION Reliance Industries Limited (IN) 2015-12-30 EP claimed
WO-2014128715-A2 AN IMPROVED MAGNESIUM DICHLORIDE SUPPORTED TITANIUM CATALYST COMPOSITION FOR POLYOLEFIN POLYMERIZATION RELIANCE INDUSTRIES LIMITED (IN) 2014-08-28 WO claimed
EP-2958950-B1 AN IMPROVED MAGNESIUM DICHLORIDE SUPPORTED TITANIUM CATALYST COMPOSITION FOR POLYOLEFIN POLYMERIZATION RELIANCE INDUSTRIES LTD (IN) 2019-09-11 EP disclosed
US-20160002372-A1 Magnesium Dichloride Supported Titanium Catalyst Composition for Polyolefin Polymerization RELIANCE INDUSTRIES LIMITED (IN) 2016-01-07 US disclosed
EP-2958950-A2 AN IMPROVED MAGNESIUM DICHLORIDE SUPPORTED TITANIUM CATALYST COMPOSITION FOR POLYOLEFIN POLYMERIZATION Reliance Industries Limited (IN) 2015-12-30 EP disclosed
WO-2014128715-A2 AN IMPROVED MAGNESIUM DICHLORIDE SUPPORTED TITANIUM CATALYST COMPOSITION FOR POLYOLEFIN POLYMERIZATION RELIANCE INDUSTRIES LIMITED (IN) 2014-08-28 WO disclosed
EP-1846366-B1 NORVALINE DERIVATIVE AND METHOD FOR PREPARATION THEREOF MITSUBISHI TANABE PHARMA CORP (JP) 2011-08-03 EP disclosed
US-7718703-B2 Norvaline derivative and method for preparation thereof MITSUBISHI TANABE PHARMA CORPORATION (JP) 2010-05-18 US disclosed
US-7718703-B2 Norvaline derivative and method for preparation thereof MITSUBISHI TANABE PHARMA CORPORATION (JP) 2010-05-18 US disclosed
US-20080076769-A1 Norvaline Derivative and Method for Preparation Thereof MITSUBISHI TANABE PHARMA CORPORATION (JP) 2008-03-27 US disclosed
US-20080076769-A1 Norvaline Derivative and Method for Preparation Thereof MITSUBISHI TANABE PHARMA CORPORATION (JP) 2008-03-27 US disclosed
EP-0758013-B1 Liquid crystalline optical film, compensating film for liquid crystal display and liquid crystal display NIPPON OIL CO LTD (JP) 2000-10-11 EP disclosed
US-5855971-A Liquid crystalline optical film, compensating film for liquid crystal display comprising the liquid crystalline optical film, and liquid crystal display having the compensating film NIPPON OIL COMPANY, LIMITED (JP) 1999-01-05 US disclosed
EP-0758013-A1 Liquid crystalline optical film, compensating film for liquid crystal display and liquid crystal display NIPPON OIL COMPANY, LIMITED (JP) 1997-02-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080076769-A1 Norvaline Derivative and Method for Preparation Thereof SLC38A7, SLC7A1, SLC6A7 KMT2A 2225/4885TP53 4367/4885TSHR 1786/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.