Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | ACACB | O00763 | 9/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13110975 | 0.91 | HDAC1 (0.57) | KDM4EALDH1A1HDAC1HDAC3HDAC2 | |
| SCHEMBL13111051 | 0.80 | RAB9A (0.52) | KDM4EALDH1A1ACACBHDAC1HDAC3 | |
| SCHEMBL8091517 | 0.80 | RAB9A (0.52) | KDM4EALDH1A1ACACBHDAC1HDAC3 | |
| SCHEMBL13110770 | 0.79 | HDAC1 (0.62) | HDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL13110983 | 0.79 | HDAC1 (0.62) | HDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL13110972 | 0.78 | HDAC1 (0.54) | HDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL24890567 | 0.74 | KDM1A (0.56) | HDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL24890712 | 0.74 | KDM1A (0.56) | HDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL24890770 | 0.74 | KDM1A (0.56) | HDAC1HDAC3HDAC2NCOR2 | |
| SCHEMBL8348119 | 0.72 | HDAC1 (0.70) | HDAC1HDAC3HDAC2NCOR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009015237-A1 | NOVEL COMPOUNDS AND METHODS OF USING THEM | SYNDAX PHARMACEUTICALS, INC. (US) | 2009-01-29 | — | — | WO | disclosed |