Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.59 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.48 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.47 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | BID | P55957 | 3/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.44 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.44 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.44 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | EP300 | Q09472 | 1/20 | 0.44 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.44 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.44 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.44 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.44 |
| ▸ | THRA | P10827 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8093678 | 0.98 | LIPG (0.62) | LIPGTLR8NR1H2NR1H3ALOX5 | |
| SCHEMBL8099869 | 0.98 | LIPG (0.62) | LIPGTLR8NR1H2NR1H3ALOX5 | |
| SCHEMBL8099162 | 0.98 | LIPG (0.62) | LIPGTLR8NR1H2NR1H3ALOX5 | |
| SCHEMBL5430739 | 0.93 | LIPG (0.50) | LIPGTLR8NR1H2NR1H3ALOX5 | |
| SCHEMBL30037094 | 0.93 | LIPG (0.65) | LIPGTLR8NR1H2NR1H3ALOX5 | |
| SCHEMBL82794 | 0.93 | LIPG (0.65) | LIPGTLR8NR1H2NR1H3ALOX5 | |
| SCHEMBL7534048 | 0.90 | LIPG (0.69) | LIPGNR1H2NR1H3ALOX5PTGS2 | |
| SCHEMBL9699968 | 0.90 | LIPG (0.69) | LIPGNR1H2NR1H3ALOX5PTGS2 | |
| SCHEMBL10755599 | 0.90 | LIPG (0.69) | LIPGNR1H2NR1H3ALOX5PTGS2 | |
| SCHEMBL18496530 | 0.90 | LIPG (0.69) | LIPGNR1H2NR1H3ALOX5PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708077-B1 | Diamino compounds and methods for preparing them | CHISSO CORP (JP) | 2000-12-27 | — | — | EP | disclosed |
| US-5663440-A | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1997-09-02 | — | — | US | disclosed |
| EP-0708077-A1 | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1996-04-24 | — | — | EP | disclosed |