⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8676221 | 0.95 | — | — | |
| SCHEMBL7642396 | 0.90 | — | — | |
| SCHEMBL10579825 | 0.90 | ALDH1A1 (0.46) | — | |
| SCHEMBL20214197 | 0.90 | — | — | |
| SCHEMBL5580867 | 0.90 | — | — | |
| SCHEMBL23295164 | 0.84 | — | — | |
| SCHEMBL2289947 | 0.84 | — | — | |
| SCHEMBL10496316 | 0.84 | — | — | |
| SCHEMBL5068410 | 0.84 | — | — | |
| SCHEMBL9357181 | 0.84 | ALDH1A1 (0.86) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0967236-B1 | Method for preparation of hydrogenmethylpolysiloxanes having trimethylsilyl endgroups | WACKER CHEMIE GMBH (DE) | 2000-11-08 | — | — | EP | claimed |
| US-6143912-A | Process for preparing methylhydrogenpolysiloxanes having trimethylsilyl end groups | WACKER-CHEMIE GMBH (DE) | 2000-11-07 | — | — | US | claimed |
| US-6143912-A | Process for preparing methylhydrogenpolysiloxanes having trimethylsilyl end groups | WACKER-CHEMIE GMBH (DE) | 2000-11-07 | — | — | US | disclosed |
| US-4140665-A | NATURAL AND SYNTHETIC LATEXES | BAYER AKTIENGESELLSCHAFT (DE) | 1979-02-20 | — | — | US | disclosed |
| US-4131603-A | Heat sensitizing mixture comprising an amide and a heat sensitizing agent which is a poly(alkylene oxide) containing urethane groups | BAYER AKTIENGESELLSCHAFT (DE) | 1978-12-26 | — | — | US | disclosed |