Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.76 |
| ▸ | NPC1 | O15118 | 8/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.76 |
| ▸ | PKM | P14618 | 3/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.76 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.76 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.76 |
| ▸ | RELA | Q04206 | 1/20 | 0.76 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.71 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.67 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | GFER | P55789 | 2/20 | 0.56 |
| ▸ | DRD2 | P14416 | 4/20 | 0.54 |
| ▸ | DRD3 | P35462 | 4/20 | 0.54 |
| ▸ | HTR1A | P08908 | 2/20 | 0.52 |
| ▸ | HTR7 | P34969 | 2/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5412145 | 0.86 | RAB9A (0.76) | RAB9ANPC1KDM4EPKMALDH1A1 | |
| SCHEMBL19322156 | 0.86 | NPC1 (0.90) | RAB9ANPC1KDM4EPKMALDH1A1 | |
| SCHEMBL8086737 | 0.86 | RAB9A (0.76) | RAB9ANPC1KDM4EPKMALDH1A1 | |
| SCHEMBL3303704 | 0.85 | NPC1 (0.74) | RAB9ANPC1KDM4EPKMALDH1A1 | |
| SCHEMBL8078651 | 0.85 | RAB9A (0.74) | RAB9ANPC1KDM4EPKMALDH1A1 | |
| SCHEMBL13325732 | 0.83 | RAB9A (1.00) | RAB9ANPC1KDM4EPKMALDH1A1 | |
| SCHEMBL7678283 | 0.82 | HRH3 (0.79) | RAB9ANPC1KDM4EPKMALDH1A1 | |
| SCHEMBL12797273 | 0.81 | RAB9A (0.71) | RAB9ANPC1KDM4EPKMALDH1A1 | |
| SCHEMBL13325926 | 0.81 | RAB9A (0.77) | RAB9ANPC1KDM4EPKMALDH1A1 | |
| SCHEMBL13325909 | 0.81 | RAB9A (0.83) | RAB9ANPC1KDM4EPKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6103724-A | EXHIBIT MAINLY ANTIPSYCHOTIC EFFECTS, E.G., SCHIZOPHRENIA, ORGANIC MENTAL DISORDERS, AFFECTIVE DISORDERS, ANXIETY, PERSONALITY DISORDERS; NEUROLEPTIC ACTIVITIY; ATYPICAL ANTIPSYCHOTICS, COGNITION ACTIVATORS, ANTIDEPRESSANTS; | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 2000-08-15 | — | — | US | disclosed |
| EP-0935599-A1 | 2-METHOXYPHENYLPIPERAZINE DERIVATIVES | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1999-08-18 | — | — | EP | disclosed |
| WO-1998018797-A1 | 2-METHOXYPHENYLPIPERAZINE DERIVATIVES | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 1998-05-07 | — | — | WO | disclosed |