Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 12/20 | 0.74 |
| ▸ | PDE5A | O76074 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4411477 | 0.85 | CNR2 (1.00) | CNR2ALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL4409934 | 0.84 | CNR2 (0.98) | CNR2ALDH1A1POLB | |
| SCHEMBL4408455 | 0.77 | CNR2 (0.63) | CNR2POLBKDM4EMAPT | |
| SCHEMBL8089503 | 0.75 | CNR2 (0.61) | CNR2ALDH1A1MAPT | |
| SCHEMBL4415634 | 0.74 | CNR2 (0.81) | CNR2ALDH1A1KDM4E | |
| SCHEMBL4544214 | 0.74 | CNR2 (0.79) | CNR2POLB | |
| SCHEMBL4415364 | 0.73 | CNR2 (0.83) | CNR2 | |
| SCHEMBL4407773 | 0.73 | CNR2 (0.81) | CNR2 | |
| SCHEMBL4408457 | 0.73 | CNR2 (1.00) | CNR2 | |
| Hydrochloric Acid SCHEMBL4408555 | 0.72 | CNR2 (0.80) | CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6017919-A | Compounds and pharmaceutical use thereof | JAPAN TOBACCO INC. (JP) | 2000-01-25 | — | — | US | disclosed |
| EP-0887340-A1 | NOVEL COMPOUNDS AND PHARMACEUTICAL USE THEREOF | Japan Tobacco Inc. (JP) | 1998-12-30 | — | — | EP | disclosed |