Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 9/20 | 0.61 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 3/20 | 0.48 |
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4408455 | 0.91 | CNR2 (0.63) | CNR2IMPDH2MAPT | |
| SCHEMBL4411502 | 0.79 | CNR2 (0.63) | CNR2MAPT | |
| SCHEMBL4409113 | 0.79 | CNR2 (0.55) | CNR2CA12CA1CA2 | |
| Hydrochloric Acid SCHEMBL8085888 | 0.79 | CNR2 (0.54) | CNR2CA12CA1CA2 | |
| SCHEMBL4414324 | 0.78 | CNR2 (0.49) | CNR2MAPT | |
| SCHEMBL4406833 | 0.78 | CNR2 (0.49) | CNR2MAPT | |
| SCHEMBL4407550 | 0.76 | CNR2 (0.53) | CNR2CA12CA1CA2 | |
| SCHEMBL4411477 | 0.76 | CNR2 (1.00) | CNR2ALDH1A1 | |
| SCHEMBL8085930 | 0.75 | CNR2 (0.74) | CNR2MAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL4409934 | 0.75 | CNR2 (0.98) | CNR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6017919-A | Compounds and pharmaceutical use thereof | JAPAN TOBACCO INC. (JP) | 2000-01-25 | — | — | US | disclosed |
| EP-0887340-A1 | NOVEL COMPOUNDS AND PHARMACEUTICAL USE THEREOF | Japan Tobacco Inc. (JP) | 1998-12-30 | — | — | EP | disclosed |