Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 14/20 | 0.71 |
| ▸ | PRSS1 | P07477 | 9/20 | 0.67 |
| ▸ | F10 | P00742 | 9/20 | 0.67 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.67 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.67 |
| ▸ | ACE | P12821 | 6/20 | 0.60 |
| ▸ | MME | P08473 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5860343 | 1.00 | F2 (0.71) | F2PRSS1F10PRSS2PRSS3 | |
| SCHEMBL10795369 | 0.77 | ACE (0.80) | ACEMME | |
| SCHEMBL10795378 | 0.77 | ACE (0.80) | ACEMME | |
| SCHEMBL6601810 | 0.77 | CASP3 (0.68) | ACEMME | |
| SCHEMBL10792401 | 0.76 | ACE (0.88) | ACEMME | |
| SCHEMBL10792409 | 0.76 | ACE (0.88) | ACEMME | |
| SCHEMBL9058169 | 0.76 | ACE (0.67) | F2ACEMME | |
| SCHEMBL8073897 | 0.76 | ACE (0.67) | F2ACEMME | |
| SCHEMBL7347032 | 0.75 | ACE (1.00) | ACEMME | |
| SCHEMBL7347023 | 0.75 | ACE (1.00) | ACEMME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6034215-A | 3-amino-2-oxo-1-piperidnercetic derivatives as enzyme inhibitors | CORVAS INTERNATIONAL, INC. (US) | 2000-03-07 | — | — | US | disclosed |
| US-5703208-A | ANTICOAGULANTS | CORVAS INTERNATIONAL, INC. (US) | 1997-12-30 | — | — | US | disclosed |
| EP-0802923-A1 | 3-AMINO-2-OXO-1-PIPERIDINEACETIC DERIVATIVES AS ENZYME INHIBITORS | CORVAS INTERNATIONAL, INC. (US) | 1997-10-29 | — | — | EP | disclosed |
| WO-1995035311-A9 | 3-AMINO-2-OXO-1-PIPERIDINEACETIC DERIVATIVES AS ENZYME INHIBITORS | — | 1996-02-01 | — | — | WO | disclosed |
| WO-1995035311-A1 | 3-AMINO-2-OXO-1-PIPERIDINEACETIC DERIVATIVES AS ENZYME INHIBITORS | CORVAS INTERNATIONAL, INC. (US) | 1995-12-28 | — | — | WO | disclosed |