Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PTPRC | P08575 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7381281 | 0.85 | MAOA (0.37) | CA12CA2CA14PTPRCL3MBTL1 | |
| SCHEMBL7381279 | 0.85 | MAOA (0.37) | CA12CA2CA14PTPRCL3MBTL1 | |
| SCHEMBL6610608 | 0.83 | MEN1 (0.41) | CA12CA2CA14PTPRCL3MBTL1 | |
| SCHEMBL15482649 | 0.82 | TET2 (0.48) | CA12CA2CA14ALDH1A1HPGD | |
| SCHEMBL9138923 | 0.78 | TSHR (0.46) | CA12CA2CA14ALDH1A1TSHR | |
| SCHEMBL18461844 | 0.78 | TDP1 (0.50) | CA12CA2ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL14365853 | 0.78 | PTPRC (0.38) | CA12CA2CA14PTPRCL3MBTL1 | |
| SCHEMBL7660758 | 0.77 | PTPRC (0.40) | CA12CA2CA14PTPRCL3MBTL1 | |
| SCHEMBL24599175 | 0.76 | SMN1; SMN2 (0.40) | ALDH1A1HPGDSMN1; SMN2ALOX15TSHR | |
| SCHEMBL23140063 | 0.74 | SMN1; SMN2 (0.44) | ALDH1A1HPGDSMN1; SMN2ALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6010680-A | Thiolation of proteins for radionuclide-based radioimmunodetection and radioimmunotherapy | IMMUNOMEDICS, INC. (US) | 2000-01-04 | — | — | US | disclosed |
| EP-0760685-A4 | THIOLATION OF PROTEINS FOR RADIONUCLIDE-BASED RADIOIMMUNODETECTION AND RADIOIMMUNOTHERAPY | IMMUNOMEDICS INC (US) | 1999-07-28 | — | — | EP | disclosed |
| US-5772981-A | Thiolation of proteins for radionuclide-based radioimmunodetection and radioimmunotherapy | IMMUNOMEDICS, INC. (US) | 1998-06-30 | — | — | US | disclosed |
| EP-0760685-A1 | THIOLATION OF PROTEINS FOR RADIONUCLIDE-BASED RADIOIMMUNODETECTION AND RADIOIMMUNOTHERAPY | Immunomedics, Inc. (US) | 1997-03-12 | — | — | EP | disclosed |
| WO-1995033495-A1 | THIOLATION OF PROTEINS FOR RADIONUCLIDE-BASED RADIOIMMUNODETECTION AND RADIOIMMUNOTHERAPY | IMMUNOMEDICS, INC. (US) | 1995-12-14 | — | — | WO | disclosed |