Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 8/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.39 |
| ▸ | KCNJ1 | P48048 | 3/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4405456 | 0.78 | CNR2 (0.76) | CNR2KCNH2KCNJ1ABCB1ABCG2 | |
| SCHEMBL8529396 | 0.72 | CNR2 (0.47) | CNR2SMN1; SMN2 | |
| SCHEMBL4418658 | 0.72 | CNR2 (0.75) | CNR2KCNH2KCNJ1HTR1AHTR1D | |
| SCHEMBL4409636 | 0.71 | CNR2 (0.76) | CNR2KCNH2KCNJ1LMNAMAPT | |
| SCHEMBL8085917 | 0.69 | CNR2 (0.51) | CNR2KCNH2KCNJ1LMNAMAPT | |
| SCHEMBL4407550 | 0.69 | CNR2 (0.53) | CNR2 | |
| SCHEMBL8085937 | 0.68 | CNR2 (0.43) | CNR2KCNH2KCNJ1ABCB1LMNA | |
| SCHEMBL4408549 | 0.66 | CNR2 (0.83) | CNR2MAPT | |
| SCHEMBL17664978 | 0.66 | ABCB1 (0.69) | KCNH2KCNJ1ABCB1ABCG2 | |
| SCHEMBL8790430 | 0.66 | ABCG2 (0.59) | KCNH2KCNJ1ABCB1ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6017919-A | Compounds and pharmaceutical use thereof | JAPAN TOBACCO INC. (JP) | 2000-01-25 | — | — | US | disclosed |