Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 11/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PDE5A | O76074 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4407550 | 0.81 | CNR2 (0.53) | CNR2L3MBTL1 | |
| SCHEMBL4409636 | 0.78 | CNR2 (0.76) | CNR2ALDH1A1SMN1; SMN2PDE5A | |
| SCHEMBL4405456 | 0.72 | CNR2 (0.76) | CNR2SMN1; SMN2 | |
| SCHEMBL8086146 | 0.72 | CNR2 (0.47) | CNR2SMN1; SMN2 | |
| SCHEMBL8085917 | 0.71 | CNR2 (0.51) | CNR2SMN1; SMN2 | |
| SCHEMBL8085930 | 0.69 | CNR2 (0.74) | CNR2ALDH1A1PDE5A | |
| SCHEMBL4407753 | 0.68 | CNR2 (0.65) | CNR2 | |
| SCHEMBL4409113 | 0.68 | CNR2 (0.55) | CNR2 | |
| SCHEMBL4411502 | 0.68 | CNR2 (0.63) | CNR2 | |
| SCHEMBL4408455 | 0.68 | CNR2 (0.63) | CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0887340-A1 | NOVEL COMPOUNDS AND PHARMACEUTICAL USE THEREOF | Japan Tobacco Inc. (JP) | 1998-12-30 | — | — | EP | disclosed |