Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.38 |
| ▸ | PTPRF | P10586 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18232224 | 0.78 | KDM4E (0.70) | ALDH1A1KDM4EHPGDHSD17B10TSHR | |
| SCHEMBL28290999 | 0.74 | ERN1 (0.50) | ALDH1A1KDM4EHPGDTSHRPOLB | |
| SCHEMBL11335017 | 0.74 | KDM4E (0.46) | ALDH1A1KDM4EHPGDHSD17B10TSHR | |
| SCHEMBL8705963 | 0.74 | ALDH1A1 (0.45) | ALDH1A1KDM4EHPGDHSD17B10TSHR | |
| SCHEMBL8875615 | 0.74 | ALDH1A1 (0.48) | ALDH1A1KDM4EHPGDHSD17B10TSHR | |
| SCHEMBL1278957 | 0.73 | ALDH1A1 (0.41) | ALDH1A1KDM4EHPGDHSD17B10TSHR | |
| SCHEMBL8902570 | 0.73 | ERN1 (0.48) | ALDH1A1KDM4EHPGDHSD17B10TSHR | |
| SCHEMBL30608694 | 0.72 | ERN1 (0.55) | ALDH1A1KDM4EHPGDTSHRPOLB | |
| SCHEMBL31632248 | 0.72 | CYP2C19 (0.69) | ALDH1A1KDM4EHPGDHSD17B10TSHR | |
| SCHEMBL11334606 | 0.71 | ALDH1A1 (0.43) | ALDH1A1KDM4EHPGDHSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6063810-A | ENANTIOMORPHS | SYNTHELABO (FR) | 2000-05-16 | — | — | US | disclosed |
| EP-0888324-A1 | 2-AMINOETHYL-BENZOFURAN DERIVATIVES, PREPARATION THEREOF AND THERAPEUTICAL USE THEREOF | SYNTHELABO (FR) | 1999-01-07 | — | — | EP | disclosed |
| WO-1997032870-A1 | 2-AMINOETHYL-BENZOFURAN DERIVATIVES, PREPARATION THEREOF AND THERAPEUTICAL USE THEREOF | SYNTHELABO (FR) | 1997-09-12 | — | — | WO | disclosed |