Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | FDPS | P14324 | 5/20 | 0.35 |
| ▸ | LAP3 | P28838 | 2/20 | 0.33 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.33 |
| ▸ | TYMS | P04818 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.31 |
| ▸ | PGK1 | P00558 | 2/20 | 0.30 |
| ▸ | PGK2 | P07205 | 2/20 | 0.30 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.30 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9683090 | 0.78 | — | — | |
| SCHEMBL11095218 | 0.75 | — | — | |
| Phosphoric Acid SCHEMBL23501797 | 0.67 | — | — | |
| SCHEMBL1409859 | 0.64 | KDM4E (0.43) | KDM4EMMP2THRBMAPK1HSD17B10 | |
| SCHEMBL919194 | 0.64 | — | — | |
| SCHEMBL4105786 | 0.64 | KDM4E (0.43) | KDM4EMMP2THRBMAPK1HSD17B10 | |
| SCHEMBL699017 | 0.64 | — | — | |
| SCHEMBL3192524 | 0.61 | — | — | |
| SCHEMBL9793676 | 0.61 | — | — | |
| Oxidronic Acid SCHEMBL393281 | 0.61 | KDM4E (0.40) | KDM4EMMP2THRBMAPK1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5442084-A | Method of selective fluorination | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1995-08-15 | — | — | US | claimed |
| EP-1038864-A1 | NOVEL METALLOPROTEINASE INHIBITORS | FUJI YAKUHIN KOGYO KABUSHIKI KAISHA (JP) | 2000-09-27 | — | — | EP | disclosed |
| EP-0479813-B1 | NOVEL METHYLENEBISPHOSPHONIC ACID DERIVATIVES | LEIRAS OY (FI) | 1995-09-20 | — | — | EP | disclosed |
| US-5442084-A | Method of selective fluorination | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1995-08-15 | — | — | US | disclosed |
| US-5376649-A | For bone disorders | LEIRAS OY (FI) | 1994-12-27 | — | — | US | disclosed |
| EP-0479813-A1 | NOVEL METHYLENEBISPHOSPHONIC ACID DERIVATIVES. | HUHTAMAEKI YHTHYMAE OY (FI) | 1992-04-15 | — | — | EP | disclosed |
| WO-1990015806-A1 | NOVEL METHYLENEBISPHOSPHONIC ACID DERIVATIVES | Huhtamäki Oy (FI) | 1990-12-27 | — | — | WO | disclosed |
| US-4689123-A | Novel tetraphosphonic acid compounds, intermediates and a process for their production | THE DOW CHEMICAL COMPANY (US) | 1987-08-25 | — | — | US | disclosed |