Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | IGF1R | P08069 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PGK1 | P00558 | 1/20 | 0.37 |
| ▸ | PGK2 | P07205 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8094146 | 0.97 | PTGS2 (0.44) | PTGS2CYP3A4IGF1RALOX15NPC1 | |
| SCHEMBL8094041 | 0.97 | PTGS2 (0.44) | PTGS2CYP3A4IGF1RALOX15NPC1 | |
| SCHEMBL8092469 | 0.97 | PTGS2 (0.44) | PTGS2CYP3A4IGF1RALOX15NPC1 | |
| SCHEMBL8093301 | 0.97 | PTGS2 (0.44) | PTGS2CYP3A4IGF1RALOX15NPC1 | |
| SCHEMBL8101181 | 0.97 | PTGS2 (0.44) | PTGS2CYP3A4IGF1RALOX15NPC1 | |
| SCHEMBL8095159 | 0.97 | PTGS2 (0.44) | PTGS2CYP3A4IGF1RALOX15NPC1 | |
| SCHEMBL8098721 | 0.97 | PTGS2 (0.44) | PTGS2CYP3A4IGF1RALOX15NPC1 | |
| SCHEMBL8100036 | 0.97 | PTGS2 (0.44) | PTGS2CYP3A4IGF1RALOX15NPC1 | |
| SCHEMBL8086884 | 0.97 | PTGS2 (0.44) | PTGS2CYP3A4IGF1RALOX15NPC1 | |
| SCHEMBL8099844 | 0.97 | PTGS2 (0.44) | PTGS2CYP3A4IGF1RALOX15NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708077-B1 | Diamino compounds and methods for preparing them | CHISSO CORP (JP) | 2000-12-27 | — | — | EP | disclosed |
| US-5663440-A | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1997-09-02 | — | — | US | disclosed |
| EP-0708077-A1 | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1996-04-24 | — | — | EP | disclosed |