SCHEMBL8086741

SCHEMBL8086741

CCC=CCCC1=C(C)CC(C)=C1

nearest known ligand 0.32

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.32
CYP19A1 P11511 2/20 0.32
RXRA P19793 2/20 0.32
PPARG P37231 2/20 0.32
OXER1 Q8TDS5 2/20 0.32
FFAR1 O14842 1/20 0.32
MAPT P10636 1/20 0.32
ADORA3 P0DMS8 2/20 0.31
NR1I2 O75469 1/20 0.31
PGR P06401 1/20 0.31
PTGS2 P35354 1/20 0.31
PDE4D Q08499 1/20 0.31
F7 P08709 1/20 0.31
F3 P13726 1/20 0.31
PTGS1 P23219 1/20 0.31
KMT2A Q03164 1/20 0.31
PPARD Q03181 1/20 0.31
PPARA Q07869 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8086778 0.82 FFAR1 (0.31) ALDH1A1CYP19A1RXRAPPARGOXER1
SCHEMBL8087999 0.71
SCHEMBL8087982 0.68
SCHEMBL6253334 0.67
SCHEMBL8088039 0.64 FFAR1 (0.31) ALDH1A1CYP19A1RXRAPPARGOXER1
SCHEMBL8079712 0.64 NOS3 (0.33)
SCHEMBL6253329 0.63
SCHEMBL692019 0.60 CYP1A2 (0.46) ALDH1A1KMT2A
SCHEMBL1083206 0.60 CYP1A2 (0.46) ALDH1A1KMT2A
Hydrochloric Acid SCHEMBL8615173 0.59

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6046346-A Production of alkali metal cyclopentadienylide and production of dihalobis (η-substituted-cyclopentadienyl) zirconium from alkali metal cyclopentadienylide HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2000-04-04 US disclosed
EP-0926150-A2 Production of alkali metal cyclopentadienylide and production of dihalobis(eta-substituted-cyclopentadienyl) zirconium from alkali metal cyclopentadienylide Honshu Chemical Industry Co. Ltd. (JP) 1999-06-30 EP disclosed