Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | KCNK3 | O14649 | 3/20 | 0.49 |
| ▸ | KCNK9 | Q9NPC2 | 3/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.46 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.46 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.46 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.46 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4252916 | 0.84 | KCNK3 (0.72) | MAPTMEN1KMT2AKCNK3KCNK9 | |
| SCHEMBL21022112 | 0.80 | MAPT (0.48) | MAPTALDH1A1MEN1KMT2AIDO1 | |
| SCHEMBL18774009 | 0.79 | KCNK3 (0.51) | MAPTALDH1A1MEN1KMT2AKCNK3 | |
| SCHEMBL12707417 | 0.78 | MEN1 (0.57) | MAPTALDH1A1MEN1KMT2AKCNK3 | |
| SCHEMBL22439869 | 0.78 | NPC1 (0.53) | MAPTMEN1KMT2AKCNK3KCNK9 | |
| SCHEMBL30619678 | 0.76 | NPSR1 (0.60) | MAPTALDH1A1MEN1KMT2AIDO1 | |
| SCHEMBL21439863 | 0.76 | NPSR1 (0.60) | MAPTALDH1A1MEN1KMT2AIDO1 | |
| SCHEMBL8085283 | 0.75 | KCNK3 (0.48) | MAPTALDH1A1MEN1KMT2AKCNK3 | |
| SCHEMBL18773854 | 0.74 | SMN1; SMN2 (0.53) | MAPTALDH1A1MEN1KMT2AKCNK3 | |
| SCHEMBL18773926 | 0.74 | TP53 (0.49) | MAPTALDH1A1MEN1KMT2AKCNK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009016088-A1 | THE USE OF BENZAMIDE DERIVATIVES FOR THE TREATMENT OF CNS DISORDERS | F. HOFFMANN-LA ROCHE AG (CH) | 2009-02-05 | — | — | WO | disclosed |