Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 11/20 | 0.48 |
| ▸ | KCNK9 | Q9NPC2 | 8/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18774009 | 0.78 | KCNK3 (0.51) | KCNK3KCNK9KCNH2MEN1KMT2A | |
| SCHEMBL12707417 | 0.77 | MEN1 (0.57) | KCNK3KCNK9KCNH2MEN1KMT2A | |
| SCHEMBL22439869 | 0.77 | NPC1 (0.53) | KCNK3KCNK9KCNH2MEN1KMT2A | |
| SCHEMBL8086756 | 0.75 | MAPT (0.50) | KCNK3KCNK9KCNH2MEN1KMT2A | |
| SCHEMBL13813895 | 0.74 | ACHE (0.50) | MEN1KMT2AHSP90AA1CYP1A2CYP3A4 | |
| SCHEMBL18773854 | 0.73 | SMN1; SMN2 (0.53) | KCNK3KCNK9KCNH2MEN1KMT2A | |
| SCHEMBL18773926 | 0.73 | TP53 (0.49) | KCNK3KCNK9KCNH2MEN1KMT2A | |
| SCHEMBL12764313 | 0.72 | KCNK3 (0.80) | KCNK3KCNK9KCNH2MEN1KMT2A | |
| SCHEMBL25543568 | 0.70 | KCNK3 (0.47) | KCNK3KCNK9KCNH2MEN1KMT2A | |
| SCHEMBL25872256 | 0.70 | ALDH1A1 (0.55) | KCNK3KCNK9KCNH2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009016088-A1 | THE USE OF BENZAMIDE DERIVATIVES FOR THE TREATMENT OF CNS DISORDERS | F. HOFFMANN-LA ROCHE AG (CH) | 2009-02-05 | — | — | WO | disclosed |