SCHEMBL8086772

SCHEMBL8086772

CC(C)(CNC(N)=O)NC(N)=O

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 1/20 0.35
ADRB1 P08588 1/20 0.35
ADRB3 P13945 1/20 0.35
TDP1 Q9NUW8 1/20 0.34
CRBN Q96SW2 1/20 0.31
EPHX1 P07099 1/20 0.31
TSHR P16473 3/20 0.30
NFKB1 P19838 2/20 0.30
CYP1A2 P05177 1/20 0.30
MAOA P21397 1/20 0.30
MAOB P27338 1/20 0.30
THPO P40225 1/20 0.30
CA2 P00918 1/20 0.30
LMNA P02545 1/20 0.30
CYP3A4 P08684 1/20 0.30
CA5A P35218 1/20 0.30
BLM P54132 1/20 0.30
PMP22 Q01453 1/20 0.30
CA9 Q16790 1/20 0.30
ALDH1A1 P00352 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12849039 0.83 ADRB2 (0.34) ADRB2ADRB1ADRB3TDP1
SCHEMBL1309452 0.81 TDP1 (0.32) ADRB2ADRB1ADRB3TDP1
SCHEMBL74035 0.79
SCHEMBL2413071 0.79 SMN1; SMN2 (0.45) ADRB2ADRB1ADRB3TDP1CRBN
SCHEMBL20686302 0.78 EPHX1 (0.41) TDP1EPHX1TSHRNFKB1LMNA
SCHEMBL4684393 0.77
SCHEMBL729760 0.77
SCHEMBL10460556 0.77
SCHEMBL1526412 0.77
SCHEMBL1667377 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6074757-A APPLYING POLYAMIDOCARBOXYLIC ACIDS AND ONE OR MORE DIAMINES AND ONE OR MORE TETETRACARBOXYLIC DIESTER TO A SUBSTRATE TO FORM A COATED SUBSTRATE AND CURING TO FORM A CURED FILM OF POLYAMIDEIMIDE COPOLYMER SCHENECTADY EUROPE GMBH (DE) 2000-06-13 US disclosed
US-5493003-A MIXTURES OF AMINES, AMIDES AND/OR ESTERS OF TETRACARBOXYLIC ACIDS HAVING AMIDO OR ESTER GROUPS SUBSTITUTED WITH CARBOXYL, SULFO, SILYL OR SILOXY GROUPS, ELECTRONICS BASF LACKE + FARBEN AKTIENGESELLSCHAFT (DE) 1996-02-20 US disclosed
US-5489644-A COMPRISING AROMATIC DIAMINES AND TETRAESTER OF AROMATIC TETRACARBOXYLIC ACID; PROTECTIVE COATING FOR METALS, SILICON WAFERS, GLASS BASF LACKE + FARBEN (DE) 1996-02-06 US disclosed
US-5478917-A Aromatic polyamines, tetracarboxylic acid amides and esters; smoothness, flexibility BASF LACKE + FARBEN AKTIENGESELLSCHAFT (DE) 1995-12-26 US disclosed
US-5332799-A Aromatic diamines, diesters of aromatic tetracarboxylic acids, circuit coatings BASF LACKE+FARBEN AKTIENGESELLSCHAFT (DE) 1994-07-26 US disclosed
US-5264545-A Aromatic or partly aromatic diamine with tetracarboxylic acid BASF LACKE+FARBEN AKTIENGESELLSCHAFT (DE) 1993-11-23 US disclosed