Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 3/20 | 0.45 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.37 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL969213 | 0.83 | MEN1 (0.51) | MAPTMEN1KMT2ALMNAGAA | |
| SCHEMBL972666 | 0.81 | TSHR (0.41) | CYP4F2CYP4A11MAPTMEN1KMT2A | |
| SCHEMBL971226 | 0.79 | ALDH1A1 (0.37) | MEN1KMT2AALDH1A1HSD17B10CYP1A2 | |
| SCHEMBL29138552 | 0.74 | CYP4F2 (0.45) | CYP4F2CYP4A11MAPTMEN1KMT2A | |
| SCHEMBL15415336 | 0.72 | CYP4F2 (0.46) | CYP4F2CYP4A11MAPTLMNAGAA | |
| SCHEMBL1081996 | 0.72 | MEN1 (0.54) | CYP4F2CYP4A11MAPTMEN1KMT2A | |
| SCHEMBL972811 | 0.71 | ALDH1A1 (0.40) | CYP4F2CYP4A11MAPTMEN1KMT2A | |
| SCHEMBL972040 | 0.71 | ALDH1A1 (0.39) | LMNAALDH1A1HSD17B10CYP1A2 | |
| SCHEMBL10735324 | 0.71 | CYP4F2 (0.49) | CYP4F2CYP4A11MAPTMEN1KMT2A | |
| SCHEMBL21063631 | 0.69 | CYP4F2 (0.50) | CYP4F2CYP4A11MAPTLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080743-A | AS CHEMICAL INTERMEIDATES FOR PREPARING DRUGS | NOVARTIS AG (CH) | 2000-06-27 | — | — | US | disclosed |
| EP-0853617-A1 | NOVEL 2,3-DIOXO-1,2,3,4-TETRAHYDRO-QUINOYXALINYL DERIVATIVES | Novartis AG (CH) | 1998-07-22 | — | — | EP | disclosed |
| WO-1997008155-A1 | NOVEL 2,3-DIOXO-1,2,3,4-TETRAHYDRO-QUINOYXALINYL DERIVATIVES | NOVARTIS AG (CH) | 1997-03-06 | — | — | WO | disclosed |