Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 16/20 | 0.52 |
| ▸ | PROC | P04070 | 2/20 | 0.47 |
| ▸ | F10 | P00742 | 1/20 | 0.47 |
| ▸ | F7 | P08709 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.43 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.39 |
| ▸ | TMPRSS11D | O60235 | 1/20 | 0.38 |
| ▸ | MASP2 | O00187 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Melagatran SCHEMBL8083301 | 0.88 | F2 (0.64) | F2PROCF10F7MASP2 | |
| Melagatran SCHEMBL23840802 | 0.88 | F2 (0.64) | F2PROCF10F7MASP2 | |
| Melagatran SCHEMBL27652 | 0.88 | F2 (0.64) | F2PROCF10F7MASP2 | |
| Melagatran SCHEMBL20567754 | 0.88 | F2 (0.64) | F2PROCF10F7MASP2 | |
| Melagatran SCHEMBL27557537 | 0.87 | F2 (0.63) | F2PROCF10F7MASP2 | |
| Melagatran SCHEMBL3209070 | 0.87 | F2 (0.63) | F2PROCF10F7MASP2 | |
| Melagatran SCHEMBL5706395 | 0.87 | F2 (0.63) | F2PROCF10F7MASP2 | |
| Melagatran SCHEMBL29160734 | 0.87 | F2 (0.63) | F2PROCF10F7MASP2 | |
| SCHEMBL23793366 | 0.86 | F2 (0.62) | F2PROCF10F7MASP2 | |
| SCHEMBL23840808 | 0.83 | F2 (0.64) | F2PROCF10F7TMPRSS11D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009018807-A9 | OXAZOLIDINONES AS FACTOR XA INHIBITORS, METHODS FOR THE PRODUCTION THEREOF, AND USE THEREOF IN THERAPY | SCHEBO BIOTECH AG (DE) | 2009-11-12 | — | — | WO | disclosed |
| WO-2009018807-A1 | NOVEL PHARMACEUTICALS, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF IN THERAPY | SCHEBO BIOTECH AG (DE) | 2009-02-12 | — | — | WO | disclosed |