Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 2/20 | 0.54 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.54 |
| ▸ | PPARA | Q07869 | 5/20 | 0.54 |
| ▸ | PPARG | P37231 | 4/20 | 0.54 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.53 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.53 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.50 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.50 |
| ▸ | THRA | P10827 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8094372 | 1.00 | LPL (0.54) | LPLLIPGPPARAPPARGSPHK2 | |
| SCHEMBL8102302 | 1.00 | LPL (0.54) | LPLLIPGPPARAPPARGSPHK2 | |
| SCHEMBL8102327 | 0.98 | LPL (0.53) | LPLLIPGPPARAPPARGSPHK2 | |
| SCHEMBL8087128 | 0.93 | CYP4F2 (0.51) | LPLLIPGPPARAPPARGSPHK2 | |
| SCHEMBL3892580 | 0.86 | KAT6A (0.50) | CYP4F2CYP4A11 | |
| SCHEMBL11434969 | 0.85 | LPL (0.55) | LPLLIPGPPARAPPARGSPHK2 | |
| SCHEMBL289254 | 0.85 | RARB (0.59) | LPLLIPGPPARAPPARGKAT8 | |
| SCHEMBL8087110 | 0.85 | LPL (0.55) | LPLLIPGPPARAPPARGSPHK2 | |
| SCHEMBL15766204 | 0.85 | RARB (0.59) | LPLLIPGPPARAPPARGKAT8 | |
| SCHEMBL1876486 | 0.85 | RARB (0.59) | LPLLIPGPPARAPPARGKAT8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708077-B1 | Diamino compounds and methods for preparing them | CHISSO CORP (JP) | 2000-12-27 | — | — | EP | disclosed |
| US-5663440-A | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1997-09-02 | — | — | US | disclosed |
| EP-0708077-A1 | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1996-04-24 | — | — | EP | disclosed |