Styrene

Styrene

SCHEMBL8087546

C=COS(=O)(=O)OC=C.C=Cc1ccccc1.c1ccccc1

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.58
TSHR P16473 1/20 0.58
TDP1 Q9NUW8 2/20 0.41
PPARG P37231 6/20 0.36
NFE2L2 Q16236 2/20 0.36
LMNA P02545 2/20 0.36
CYP2A6 P11509 1/20 0.36
HDAC8 Q9BY41 2/20 0.35
MCL1 Q07820 1/20 0.33
TP53 P04637 1/20 0.33
CYP1A2 P05177 1/20 0.32
TRPA1 O75762 1/20 0.31
ALOX5 P09917 1/20 0.31
MAPK1 P28482 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL29154502 0.84 ALDH1A1 (0.54) ALDH1A1TSHRTDP1PPARGNFE2L2
Biphenyl SCHEMBL4534585 0.83 ALDH1A1 (0.41) ALDH1A1TSHR
Styrene SCHEMBL875079 0.82 ALDH1A1 (0.52) ALDH1A1TSHRTDP1PPARGNFE2L2
Styrene SCHEMBL9453760 0.78 ALDH1A1 (0.64) ALDH1A1TSHRTDP1LMNACYP2A6
Styrene SCHEMBL5872181 0.78 ALDH1A1 (0.70) ALDH1A1TSHRTDP1PPARGNFE2L2
Styrene SCHEMBL1261405 0.78 ALDH1A1 (0.70) ALDH1A1TSHRTDP1LMNACYP2A6
Styrene SCHEMBL15366649 0.78 ALDH1A1 (0.70) ALDH1A1TSHRTDP1PPARGNFE2L2
Styrene SCHEMBL1456347 0.78 ALDH1A1 (0.70) ALDH1A1TSHRTDP1PPARGNFE2L2
Styrene SCHEMBL347858 0.78 ALDH1A1 (0.70) ALDH1A1TSHRTDP1PPARGNFE2L2
Styrene SCHEMBL27738737 0.78 ALDH1A1 (0.70) ALDH1A1TSHRTDP1PPARGNFE2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1045825-A1 NOVEL POLYETHOXYLATED CASTOR OIL, PROCESS OF MAKING THE SAME AND FORMULATIONS THEREOF Schein Pharmaceutical, Inc. (US) 2000-10-25 EP disclosed
US-5925776-A LOW SODIUM, POTASSIUM, AND ALUMINUM CATION CONTENT; STORAGE STABILITY; EXPOSING TO CATIONIC EXCHANGE RESIN SCHEIN PHARMACETICAL, INC. (US) 1999-07-20 US disclosed
WO-1999033780-A1 NOVEL POLYETHOXYLATED CASTOR OIL, PROCESS OF MAKING THE SAME AND FORMULATIONS THEREOF SCHEIN PHARMACEUTICAL, INC. (US) 1999-07-08 WO disclosed