Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 2/20 | 0.58 |
| ▸ | GRK5 | P34947 | 2/20 | 0.58 |
| ▸ | TYRO3 | Q06418 | 2/20 | 0.58 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.58 |
| ▸ | CA12 | O43570 | 15/20 | 0.46 |
| ▸ | CA9 | Q16790 | 15/20 | 0.46 |
| ▸ | CA2 | P00918 | 14/20 | 0.46 |
| ▸ | CA1 | P00915 | 11/20 | 0.43 |
| ▸ | CA7 | P43166 | 11/20 | 0.43 |
| ▸ | CA4 | P22748 | 9/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7014198 | 0.80 | RET (0.57) | RETGRK5TYRO3DYRK1BCA12 | |
| SCHEMBL9448490 | 0.77 | RET (0.38) | RETGRK5TYRO3DYRK1BCA12 | |
| SCHEMBL7281756 | 0.76 | RET (0.53) | RETGRK5TYRO3DYRK1BCA12 | |
| SCHEMBL9407224 | 0.75 | RET (0.51) | RETGRK5TYRO3DYRK1BCA12 | |
| SCHEMBL7281544 | 0.75 | RET (0.51) | RETGRK5TYRO3DYRK1BCA12 | |
| SCHEMBL7381362 | 0.74 | RET (0.62) | RETGRK5TYRO3DYRK1BCA12 | |
| SCHEMBL1725776 | 0.74 | RET (1.00) | RETGRK5TYRO3DYRK1BCA12 | |
| SCHEMBL7287920 | 0.74 | RET (0.50) | RETGRK5TYRO3DYRK1BCA12 | |
| SCHEMBL11155230 | 0.73 | RET (0.61) | RETGRK5TYRO3DYRK1BCA12 | |
| SCHEMBL7023285 | 0.70 | RET (0.62) | RETGRK5TYRO3DYRK1BCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0538784-B2 | Pigment preparations | CLARIANT GMBH (DE) | 2000-12-27 | — | — | EP | disclosed |
| US-5264032-A | Saccharine derivatives of pigments as dispersants | HOECHST AG (DE) | 1993-11-23 | — | — | US | disclosed |
| EP-0538784-A1 | Pigment preparations | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-04-28 | — | — | EP | disclosed |