Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 2/20 | 0.38 |
| ▸ | GRK5 | P34947 | 2/20 | 0.38 |
| ▸ | TYRO3 | Q06418 | 2/20 | 0.38 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 3/20 | 0.34 |
| ▸ | CA9 | Q16790 | 3/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9448309 | 0.65 | CA9 (0.35) | CA12CA9CA2KDM4EUSP2 | |
| SCHEMBL9179277 | 0.62 | RET (0.53) | RETGRK5TYRO3DYRK1BCA12 | |
| SCHEMBL7279275 | 0.61 | CA12 (0.52) | RETGRK5TYRO3DYRK1BCA12 | |
| SCHEMBL2802516 | 0.59 | RET (0.41) | RETGRK5TYRO3DYRK1BCHEK1 | |
| SCHEMBL995389 | 0.58 | CA12 (0.50) | RETGRK5TYRO3DYRK1BCA12 | |
| Saccharin SCHEMBL27770477 | 0.58 | CA12 (0.85) | RETGRK5TYRO3DYRK1BCA12 | |
| SCHEMBL230481 | 0.58 | CA9 (0.50) | RETGRK5TYRO3DYRK1BCA12 | |
| SCHEMBL2804664 | 0.58 | RET (0.44) | RETGRK5TYRO3DYRK1BCA12 | |
| Saccharin SCHEMBL28873599 | 0.58 | CA12 (0.73) | RETGRK5TYRO3DYRK1BCA12 | |
| SCHEMBL29689422 | 0.56 | RET (0.46) | RETGRK5TYRO3DYRK1BCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5264032-A | Saccharine derivatives of pigments as dispersants | HOECHST AG (DE) | 1993-11-23 | — | — | US | disclosed |
| EP-0538784-A1 | Pigment preparations | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-04-28 | — | — | EP | disclosed |