Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.45 |
| ▸ | THPO | P40225 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.45 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8603803 | 0.84 | MAPT (0.67) | MAPTALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL9018579 | 0.82 | MAPT (0.47) | MAPTALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL8393788 | 0.81 | MAPT (0.69) | MAPTALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL11797834 | 0.78 | MAPT (0.68) | MAPTALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL8084364 | 0.78 | TSHR (0.43) | MAPTALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL10352579 | 0.77 | MEN1 (0.61) | MAPTMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL10652678 | 0.76 | CYP1A2 (0.49) | MAPTMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL10655983 | 0.76 | CYP1A2 (0.47) | MAPTMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL10652165 | 0.75 | CYP1A2 (0.48) | MAPTMEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL11317222 | 0.74 | MEN1 (0.57) | MAPTMEN1KMT2ACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0758647-A1 | Acyl substituted aminopyrans with a modulating effect on calcium channels | BAYER AG (DE) | 1997-02-19 | — | — | EP | claimed |
| EP-0758647-B1 | Acyl substituted aminopyrans with a modulating effect on calcium channels | BAYER AG (DE) | 2000-11-02 | — | — | EP | disclosed |
| EP-0758647-A1 | Acyl substituted aminopyrans with a modulating effect on calcium channels | BAYER AG (DE) | 1997-02-19 | — | — | EP | disclosed |