Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CCR1 | P32246 | 9/20 | 0.39 |
| ▸ | LSS | P48449 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | DRD4 | P21917 | 2/20 | 0.35 |
| ▸ | DRD3 | P35462 | 2/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | DRD5 | P21918 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8083776 | 0.86 | DRD2 (0.38) | DRD2DRD4DRD3DRD1DRD5 | |
| SCHEMBL7754639 | 0.86 | ESR2 (0.42) | DRD2 | |
| SCHEMBL7755527 | 0.82 | CYP2C9 (0.40) | DRD2CCR1 | |
| SCHEMBL7757153 | 0.82 | DRD2 (0.35) | DRD2CCR1 | |
| SCHEMBL8040058 | 0.79 | DRD2 (0.35) | DRD2MEN1KMT2ACCR1 | |
| SCHEMBL7755480 | 0.77 | ESR2 (0.40) | — | |
| SCHEMBL8580088 | 0.76 | AKR1C2 (0.34) | DRD2DRD5 | |
| SCHEMBL8580084 | 0.76 | AKR1C2 (0.34) | DRD2DRD5 | |
| SCHEMBL8027799 | 0.76 | SPHK1 (0.37) | DRD2 | |
| SCHEMBL8944805 | 0.75 | NPC1 (0.33) | DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0673942-B1 | Silacyclohexanone compounds as intermediates for the preparation of silacyclohexane-type liquid cristal compounds | SHINETSU CHEMICAL CO (JP) | 2000-11-08 | — | — | EP | disclosed |
| US-5641431-A | Silacyclohexanone compound and a method of preparing a silacyclohexane-type liquid crystal composition containing it | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1997-06-24 | — | — | US | disclosed |
| EP-0673942-A1 | Silacyclohexanone compounds as intermediates for the preparation of silacyclohexane-type liquid cristal compounds | Shin-Etsu Chemical Co., Ltd. (JP) | 1995-09-27 | — | — | EP | disclosed |