Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNRHR | P30968 | 20/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8088012 | 1.00 | GNRHR (0.80) | GNRHR | |
| SCHEMBL7977286 | 0.86 | GNRHR (0.81) | GNRHR | |
| SCHEMBL7977280 | 0.86 | GNRHR (0.81) | GNRHR | |
| SCHEMBL8437794 | 0.85 | GNRHR (0.59) | GNRHR | |
| SCHEMBL8437799 | 0.85 | GNRHR (0.59) | GNRHR | |
| SCHEMBL8079137 | 0.81 | GNRHR (0.61) | GNRHR | |
| SCHEMBL7858393 | 0.78 | GNRHR (0.49) | GNRHR | |
| SCHEMBL8012586 | 0.78 | GNRHR (0.49) | GNRHR | |
| SCHEMBL6983762 | 0.77 | GNRHR (0.78) | GNRHR | |
| SCHEMBL8026780 | 0.75 | GNRHR (0.51) | GNRHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6077847-A | ADMINISTERING A SUBSTITUTED INDOLE COMPOUND TO THE PATIENTS FOR THE TREATMENT OF A VARIETY OF SEX-HORMONE RELATED AND OTHER CONDITIONS IN BOTH MEN AND WOMEN | MERCK & CO., INC. (US) | 2000-06-20 | — | — | US | disclosed |