SCHEMBL8088092

SCHEMBL8088092

Sc1nccs1.[NaH]

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23753 0.97
SCHEMBL10533757 0.94 ALDH1A1 (0.46)
SCHEMBL17977839 0.94
SCHEMBL5375407 0.94
SCHEMBL30753571 0.94
Pyridine SCHEMBL27729484 0.83 TSHR (0.41)
Hydrochlorthiazide SCHEMBL20873795 0.79 ALDH1A1 (0.34)
SCHEMBL7108032 0.78 ALDH1A1 (0.33)
Chlorobenzene SCHEMBL27490190 0.78 TSHR (0.44)
SCHEMBL11509016 0.76 PDPK1 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0299942-B1 ANTIFREEZE COMPOSITION NIPPON SHOKUBAI CO., LTD. (JP) 1992-12-02 EP claimed
EP-0299942-A2 Antifreeze composition NIPPON SHOKUBAI CO., LTD. (JP) 1989-01-18 EP claimed
US-12409680-B2 Functionalized polymers tread additive for improved winter tire performance EXXONMOBIL CHEMICAL PATENTS INC. (US) 2025-09-09 US disclosed
EP-4077527-B1 FUNCTIONALIZED POLYMERS TREAD ADDITIVE FOR IMPROVED WET BRAKING AND ROLLING RESISTANCE IN LOW SILICA SUMMER TIRE EXXONMOBIL CHEMICAL PATENTS INC (US) 2024-09-18 EP disclosed
CN-114846070-B Functionalized polymer tread additives for improving wet skid braking and rolling resistance of high silica summer tires 埃克森美孚化学专利公司 2024-09-13 CN disclosed
CN-114846069-B Functionalized polymer tread additives for improving wet skid braking and rolling resistance of low silica summer tires 埃克森美孚化学专利公司 2024-08-27 CN disclosed
CN-112074546-B Solvent-free process for functionalizing isobutylene-based polymers 埃克森美孚化学专利公司 2024-05-28 CN disclosed
CN-114901490-B Functionalized polymer tread additives for improving winter tyre performance 埃克森美孚化学专利公司 2024-03-15 CN disclosed
US-20230278367-A1 Functionalized Polymers Tread Additive For Improved Winter Tire Performance EXXONMOBIL CHEMICAL PATENTS INC (US) 2023-09-07 US disclosed
US-20230029797-A1 Functionalized Polymers Tread Additive For Improved Wet Braking And Rolling Resistance In Low Silica Summer Tire EXXONMOBIL CHEMICAL PATENTS INC (US) 2023-02-02 US disclosed
US-20230022627-A1 Functionalized Polymers Tread Additive For Improved Wet Braking And Rolling Resistance In High Silica Summer Tire EXXONMOBIL CHEMICAL PATENTS INC (US) 2023-01-26 US disclosed
CN-107353297-A A kind of efficient Ceftaroline Fosamil synthetic method 郑州大学 2017-11-17 CN disclosed
CN-104725425-B A kind of preparation method of Ceftaroline Fosamil 山东罗欣药业集团股份有限公司 2017-01-04 CN disclosed
CN-104725425-A Preparation method for ceftaroline fosamil SHANDONG LUOXIN PHARMACEUTICAL GROUP CO LTD 2015-06-24 CN disclosed
CN-102459196-A Novel process for the preparation of rosuvastatin, intermediate compounds useful for the preparation of rosuvastatin, and processes for the preparation of said intermediate compounds CHONG KUN DANG PHARM CORP 2012-05-16 CN disclosed
CN-1189471-C Phosphonocephem compound TAKEDA CHEMICAL INDUSTRIES LTD (JP) 2005-02-16 CN disclosed
CN-1462275-A Phosphonocephem compound TAKEDA CHEMICAL INDUSTRIES LTD (JP) 2003-12-17 CN disclosed
EP-0514649-B1 Stabilization of aqueous solutions of watersoluble polymers in the presence of hydroxylamine CYTEC TECH CORP (US) 2000-10-25 EP disclosed
EP-0299942-B1 ANTIFREEZE COMPOSITION NIPPON SHOKUBAI CO., LTD. (JP) 1992-12-02 EP disclosed
EP-0514649-A1 Stabilization of aqueous polymers in the presence of hydroxylamine CYTEC TECHNOLOGY CORP. (US) 1992-11-25 EP disclosed