Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | P2RX3 | P56373 | 15/20 | 0.45 |
| ▸ | P2RX2 | Q9UBL9 | 15/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8097905 | 0.89 | KDM4E (0.46) | KDM4EALDH1A1LMNAHTTPOLB | |
| SCHEMBL8088148 | 0.88 | P2RX3 (0.47) | P2RX3P2RX2 | |
| SCHEMBL2861794 | 0.84 | P2RX3 (0.61) | P2RX3P2RX2 | |
| SCHEMBL8096800 | 0.76 | P2RX3 (0.79) | P2RX3P2RX2 | |
| SCHEMBL997980 | 0.75 | P2RX3 (0.61) | P2RX3 | |
| SCHEMBL2863803 | 0.74 | P2RX3 (0.63) | P2RX3P2RX2 | |
| SCHEMBL8096754 | 0.74 | P2RX3 (0.80) | P2RX3P2RX2 | |
| SCHEMBL8094929 | 0.74 | P2RX3 (0.80) | P2RX3P2RX2 | |
| SCHEMBL8104653 | 0.73 | P2RX3 (0.80) | P2RX3P2RX2 | |
| SCHEMBL14003523 | 0.73 | P2RX3 (0.52) | P2RX3P2RX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008130481-A1 | 2-CYANOPHENYL FUSED HETEROCYCLIC COMPOUNDS, AND COMPOSITIONS AND USES THEREOF | RENOVIS, INC. (US) | 2008-10-30 | — | — | WO | disclosed |