Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | CCR2 | P41597 | 1/20 | 0.39 |
| ▸ | FNTA | P49354 | 10/20 | 0.39 |
| ▸ | FNTB | P49356 | 9/20 | 0.39 |
| ▸ | PGGT1B | P53609 | 7/20 | 0.39 |
| ▸ | CCR5 | P51681 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL446560 | 0.92 | FNTA (0.45) | CCR2FNTAFNTBPGGT1BCCR5 | |
| SCHEMBL8095888 | 0.91 | FNTA (0.42) | CCR2FNTAFNTBPGGT1BCCR5 | |
| SCHEMBL8097456 | 0.91 | FNTA (0.44) | FNTAFNTBPGGT1BCCR5KCNH2 | |
| SCHEMBL8095365 | 0.90 | KDM4E (0.47) | KDM4EOPRM1OPRD1CCR2FNTA | |
| SCHEMBL8095560 | 0.89 | FNTA (0.41) | CCR2FNTAFNTBPGGT1BCCR5 | |
| SCHEMBL8095468 | 0.88 | FNTA (0.43) | CCR2FNTAFNTBPGGT1BCCR5 | |
| SCHEMBL8097931 | 0.87 | KMT2A (0.51) | CCR2FNTAFNTBPGGT1BCCR5 | |
| SCHEMBL8101380 | 0.86 | FNTA (0.43) | CCR2FNTAFNTBPGGT1BCCR5 | |
| SCHEMBL8088419 | 0.86 | FNTA (0.47) | FNTAFNTBPGGT1BKCNH2 | |
| SCHEMBL8436084 | 0.86 | FNTA (0.47) | FNTAFNTBPGGT1BKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127366-A | ANTICARCINOGENIC OR ANTITUMOR AGENTS | MERCK & CO., INC. (US) | 2000-10-03 | — | — | US | disclosed |