Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 16/20 | 0.41 |
| ▸ | FNTB | P49356 | 16/20 | 0.41 |
| ▸ | PGGT1B | P53609 | 12/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.41 |
| ▸ | CCR5 | P51681 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CCR2 | P41597 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL446560 | 0.93 | FNTA (0.45) | FNTAFNTBPGGT1BKCNH2CCR5 | |
| SCHEMBL8095888 | 0.92 | FNTA (0.42) | FNTAFNTBPGGT1BKCNH2CCR5 | |
| SCHEMBL8097456 | 0.92 | FNTA (0.44) | FNTAFNTBPGGT1BKCNH2CCR5 | |
| SCHEMBL8095468 | 0.90 | FNTA (0.43) | FNTAFNTBPGGT1BKCNH2CCR5 | |
| SCHEMBL8088415 | 0.89 | KDM4E (0.41) | FNTAFNTBPGGT1BKCNH2CCR5 | |
| SCHEMBL8097931 | 0.88 | KMT2A (0.51) | FNTAFNTBPGGT1BKCNH2CCR5 | |
| SCHEMBL8101380 | 0.88 | FNTA (0.43) | FNTAFNTBPGGT1BKCNH2CCR5 | |
| SCHEMBL8095566 | 0.86 | FNTA (0.49) | FNTAFNTBPGGT1BKCNH2CYP3A4 | |
| SCHEMBL8426008 | 0.86 | FNTA (0.49) | FNTAFNTBPGGT1BKCNH2CYP3A4 | |
| SCHEMBL8095903 | 0.85 | CYP11B1 (0.45) | FNTAFNTBPGGT1BKCNH2CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127366-A | ANTICARCINOGENIC OR ANTITUMOR AGENTS | MERCK & CO., INC. (US) | 2000-10-03 | — | — | US | disclosed |