Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.52 |
| ▸ | HTR2A | P28223 | 2/20 | 0.52 |
| ▸ | HTR2B | P41595 | 2/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
| ▸ | MTNR1A | P48039 | 9/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 9/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.38 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8088680 | 1.00 | HTR2C (0.52) | HTR2CSLC6A4HTR2AHTR2BSLC6A3 | |
| SCHEMBL8098166 | 0.86 | HTR2C (0.51) | HTR2CHTR2AHTR2BMTNR1AMTNR1B | |
| SCHEMBL8098167 | 0.86 | HTR2C (0.51) | HTR2CHTR2AHTR2BMTNR1AMTNR1B | |
| SCHEMBL8098497 | 0.85 | HTR2C (0.56) | HTR2CSLC6A4HTR2AHTR2BSLC6A3 | |
| SCHEMBL8098498 | 0.85 | HTR2C (0.56) | HTR2CSLC6A4HTR2AHTR2BSLC6A3 | |
| SCHEMBL8088502 | 0.84 | HTR2A (0.56) | HTR2CHTR2AHTR2BMTNR1AMTNR1B | |
| SCHEMBL8088503 | 0.84 | HTR2A (0.56) | HTR2CHTR2AHTR2BMTNR1AMTNR1B | |
| SCHEMBL8102259 | 0.83 | HTR2C (0.54) | HTR2CHTR2AHTR2BMTNR1AMTNR1B | |
| SCHEMBL8102256 | 0.83 | HTR2C (0.54) | HTR2CHTR2AHTR2BMTNR1AMTNR1B | |
| SCHEMBL8095382 | 0.81 | MTNR1B (0.52) | HTR2CSLC6A4HTR2AHTR2BSLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0747346-B1 | N-acyl-2 aryl cyclopropylmethylamine derivatives as melatonergics | BRISTOL MYERS SQUIBB CO (US) | 2000-02-16 | — | — | EP | disclosed |
| EP-0747346-A2 | N-acyl-2 aryl cyclopropylmethylamine derivatives as melatonergics | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-12-11 | — | — | EP | disclosed |