SCHEMBL8088686

SCHEMBL8088686

CC(OC(=O)C(=O)OC(C)c1ccccc1)c1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 1/20 0.61
KMT2A Q03164 1/20 0.47
ALDH1A1 P00352 2/20 0.46
TP53 P04637 1/20 0.46
HSD17B10 Q99714 1/20 0.46
FFAR1 O14842 1/20 0.45
CYP2D6 P10635 1/20 0.44
SRC P12931 1/20 0.44
CYP3A4 P08684 1/20 0.44
ESR1 P03372 1/20 0.44
ESR2 Q92731 1/20 0.44
LPAR1 Q92633 2/20 0.43
LPAR3 Q9UBY5 1/20 0.43
LMNA P02545 2/20 0.43
MAPK1 P28482 1/20 0.43
ALOX5 P09917 2/20 0.42
TSHR P16473 1/20 0.42
GABRA1 P14867 1/20 0.42
GABRG2 P18507 1/20 0.42
GABRB3 P28472 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7701591 0.91 HCAR2 (0.58) HCAR2KMT2AALDH1A1TP53HSD17B10
SCHEMBL16085915 0.90 HCAR2 (0.56) HCAR2KMT2AALDH1A1TP53HSD17B10
SCHEMBL3625229 0.86 HCAR2 (0.61) HCAR2KMT2AALDH1A1TP53HSD17B10
SCHEMBL3786371 0.86 HCAR2 (0.61) HCAR2KMT2AALDH1A1TP53HSD17B10
SCHEMBL3625234 0.86 HCAR2 (0.61) HCAR2KMT2AALDH1A1TP53HSD17B10
SCHEMBL3786370 0.86 HCAR2 (0.61) HCAR2KMT2AALDH1A1TP53HSD17B10
SCHEMBL871943 0.86 HCAR2 (0.61) HCAR2KMT2AALDH1A1TP53HSD17B10
SCHEMBL1694877 0.86 HCAR2 (0.61) HCAR2KMT2AALDH1A1TP53HSD17B10
SCHEMBL16194609 0.86 HCAR2 (0.53) HCAR2ALDH1A1TP53HSD17B10CYP3A4
SCHEMBL10907558 0.86 HCAR2 (0.53) HCAR2KMT2AALDH1A1TP53HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6031021-A SINGLE SUPPLY THERMAL TRANSFER MEDIUM WHICH CAN FORM PRINTED IMAGES IN A RANGE OF COLORS WITH A MULTIHEAD PRINTER AT VARIED PRINT HEAD SETTINGS USING A EPOXIDIZED PHENOLIC RESIN BINDER BASED ON CRESOL AND METHYLPHENOL COMPOUND; EFFICIENCY NCR CORPORATION (US) 2000-02-29 US disclosed
EP-0665960-B1 IMAGING MEDIUM AND PROCESS POLAROID CORP (US) 1998-08-19 EP disclosed
EP-0561558-B1 Thermal recording sheet JUJO PAPER CO LTD (JP) 1998-05-13 EP disclosed
EP-0559386-B1 Thermal recording sheet JUJO PAPER CO LTD (JP) 1997-01-15 EP disclosed
US-5578424-A EXPOSING A MIXTURE OF AN ACID PRECURSOR AND A DYE TO ACTINIC RADIATION TO DECOMPOSE PRECURSOR POLAROID CORPORATION (US) 1996-11-26 US disclosed
EP-0665961-B1 IMAGING MEDIUM AND PROCESS POLAROID CORP (US) 1996-10-02 EP disclosed
US-5534388-A SUPERACID PRECURSOR IS EXPOSED TO ACTINIC RADIATION TO GENERATE SUPERACID; COLORIMETRIC ANALYSIS POLAROID CORPORATION (US) 1996-07-09 US disclosed
US-5453345-A Imaging medium POLAROID CORPORATION (US) 1995-09-26 US disclosed
US-5445917-A Superacid precursor to catalyze thermal decomposition of secondary acid generator, such as squaric acid and oxalic acid derivatives; effecting color change in imaging process POLAROID CORPORATION (US) 1995-08-29 US disclosed
US-5395736-A Exposing superoxide precursor to actinic radiation, generating superacid, mixing with oxalic acid diester, heating POLAROID CORPORATION (US) 1995-03-07 US disclosed
US-5352650-A Heat/oil/weather and water resistance, storage stability, photosensitivity; used in computer terminal printers, facsimiles, automatic ticket vendors, bar-code labels, and measurement recorders JUJO PAPER CO., LTD. (JP) 1994-10-04 US disclosed
US-5322831-A Color developers, chromogenic dye, stabilizer and sensitizer JUJO PAPER CO., LTD. (JP) 1994-06-21 US disclosed
EP-0561558-A2 Thermal recording sheet NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1993-09-22 EP disclosed
EP-0559386-A2 Thermal recording sheet NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1993-09-08 EP disclosed