Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.72 |
| ▸ | F2R | P25116 | 9/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20183907 | 0.90 | MEN1 (0.68) | MEN1KMT2AALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL4135856 | 0.88 | MEN1 (0.64) | MEN1KMT2AALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL10975643 | 0.88 | F2R (0.73) | F2RALDH1A1POLBMTNR1BMAPT | |
| SCHEMBL31329492 | 0.87 | MEN1 (0.72) | MEN1KMT2AF2RALDH1A1POLB | |
| SCHEMBL4050787 | 0.87 | MEN1 (0.72) | MEN1KMT2AF2RALDH1A1POLB | |
| SCHEMBL2608527 | 0.86 | KMT2A (0.77) | MEN1KMT2AALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL11756097 | 0.83 | POLB (0.72) | MEN1KMT2AF2RALDH1A1POLB | |
| SCHEMBL2712100 | 0.82 | TP53 (0.56) | MEN1KMT2AF2RALDH1A1MAPT | |
| SCHEMBL882804 | 0.82 | KMT2A (0.72) | MEN1KMT2AF2RALDH1A1SMN1; SMN2 | |
| SCHEMBL5541810 | 0.81 | F2R (0.61) | F2RALDH1A1MTNR1BMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119968368-A | Amide compound, preparation method, pharmaceutical composition and application thereof | 中国科学院上海药物研究所 | 2025-05-09 | — | — | CN | disclosed |
| CN-117402156-A | Amide compound, preparation method, pharmaceutical composition and application thereof | 中国科学院上海药物研究所 | 2024-01-16 | — | — | CN | disclosed |
| WO-2024008196-A1 | CLASS OF AMIDE COMPOUNDS AND PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | 中国科学院上海药物研究所 | 2024-01-11 | — | — | WO | disclosed |
| CN-108026056-A | As the 1,3,4- oxadiazole amide derivative compounds of 6 inhibitor of histone deacetylase and the pharmaceutical composition containing it | 株式会社钟根堂 | 2018-05-11 | — | — | CN | disclosed |
| EP-1042275-A1 | ANTICONVULSANT AND CENTRAL NERVOUS SYSTEM-ACTIVE BIS(FLUOROPHENYL)ALKYLAMIDES | NPS PHARMACEUTICALS, INC. (US) | 2000-10-11 | — | — | EP | disclosed |
| WO-1999029657-A1 | ANTICONVULSANT AND CENTRAL NERVOUS SYSTEM-ACTIVE BIS(FLUOROPHENYL)ALKYLAMIDES | NPS PHARMACEUTICALS, INC. (US) | 1999-06-17 | — | — | WO | disclosed |